2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Chemokine & Receptors
  5. CXC Chemokines
  6. MIP-2/GRO-beta
  7. GRO-beta/CXCL2 Protein, Human (HEK293, hFc)

GRO-beta/CXCL2 Protein, Human (HEK293, hFc)

Cat. No.: HY-P704371
Handling Instructions Technical Support

GRO-beta/CXCL2 Protein, generated by activated monocytes and neutrophils, is prominently expressed at inflammatory sites. Notably, this chemokine, with hematoregulatory properties, suppresses hematopoietic progenitor cell proliferation in vitro. GRO-beta(5-73) displays heightened hematopoietic activity, emphasizing its significant role in regulating hematopoiesis. GRO-beta/CXCL2 Protein, Human (HEK293, hFc) is the recombinant human-derived GRO-beta/CXCL2 protein, expressed by HEK293, with C-hFc labeled tag.

For research use only. We do not sell to patients.

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Description

GRO-beta/CXCL2 Protein, generated by activated monocytes and neutrophils, is prominently expressed at inflammatory sites. Notably, this chemokine, with hematoregulatory properties, suppresses hematopoietic progenitor cell proliferation in vitro. GRO-beta(5-73) displays heightened hematopoietic activity, emphasizing its significant role in regulating hematopoiesis. GRO-beta/CXCL2 Protein, Human (HEK293, hFc) is the recombinant human-derived GRO-beta/CXCL2 protein, expressed by HEK293, with C-hFc labeled tag.
Background

GRO-beta/CXCL2, generated by activated monocytes and neutrophils, is prominently expressed at sites of inflammation. This chemokine exhibits hematoregulatory properties, as it has been observed to suppress the proliferation of hematopoietic progenitor cells in vitro. Particularly noteworthy is the heightened hematopoietic activity displayed by GRO-beta(5-73), emphasizing its significant role in regulating hematopoiesis.
Species

Human
Source

HEK293
Tag

C-hFc
Accession

P19875 (A35-N107)
Gene ID

2920
Molecular Construction
N-term
CXCL2 (A35-N107)
Accession # P19875
hFc
C-term
Protein Length

Full Length of Mature Protein
Synonyms
GRO-β/CXCL2; C-X-C motif chemokine 2; MIP2-alpha; HSF
Predicted Molecular Mass
34.3 kDa
Molecular Weight

Approximately 38-42 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Glycosylation
Yes
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

GRO-beta/CXCL2 Protein, Human (HEK293, hFc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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