2. PI3K/Akt/mTOR
  3. PI3K
  4. GSK2636771 (Standard)

GSK2636771 (Standard) is the analytical standard of GSK2636771. This product is intended for research and analytical applications. GSK2636771 is a potent, selective and orally bioavailable inhibitor of PI3Kβ with a Ki of 0.89 nM and an IC50 of 5.2 nM, showing 900-fold selectivity over p110α and p110γ, and 10-fold selectivity over p110δ isoforms.

For research use only. We do not sell to patients.

GSK2636771 (Standard) Chemical Structure

GSK2636771 (Standard) Chemical Structure

CAS No. : 1372540-25-4

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Description

GSK2636771 (Standard) is the analytical standard of GSK2636771. This product is intended for research and analytical applications. GSK2636771 is a potent, selective and orally bioavailable inhibitor of PI3Kβ with a Ki of 0.89 nM and an IC50 of 5.2 nM, showing 900-fold selectivity over p110α and p110γ, and 10-fold selectivity over p110δ isoforms.

Molecular Weight

433.42

Formula

C22H22F3N3O3
CAS No.
SMILES

CC1=NC2=C(C(O)=O)C=C(C=C2N1CC3=CC=CC(C(F)(F)F)=C3C)N4CCOCC4
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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GSK2636771 (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GSK2636771 (Standard)1372540-25-4PI3KPhosphoinositide 3-kinaseInhibitorinhibitorinhibit

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