2. Others Membrane Transporter/Ion Channel Neuronal Signaling
  3. Reference Standards GABA Receptor
  4. FG 7142 (Standard)

FG 7142 (Standard)  (Synonyms: ZK 39106 (Standard); LSU-65 (Standard))

Cat. No.: HY-100991R Purity: ≥98%
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FG 7142 (Standard) is the analytical standard of FG 7142. This product is intended for research and analytical applications. FG 7142 (ZK 39106; LSU-65), a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM). FG 7142 (ZK 39106; LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 (ZK 39106; LSU-65) can increase tyrosine hydroxylation and cause upregulation of?β-adrenoceptors in mouse cerebral cortex.

For research use only. We do not sell to patients.

FG 7142 (Standard) Chemical Structure

FG 7142 (Standard) Chemical Structure

CAS No. : 78538-74-6

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FG 7142 (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FG 7142 (Standard)78538-74-6ZK 39106 (Standard)LSU-65 (Standard)Reference StandardsGABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid Receptorinverse agonistdopaminergic tyrosine hydroxylasenucleus accumbenGABAA receptorInhibitorinhibitorinhibit

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