TFAP2A Antibody (YA3659)

TFAP2A Antibody (YA3659) is a mouse-derived and non-conjugated IgG1 antibody, targeting to TFAP2A. It can be applicated for WB, ICC/IF, FC, ELISA assays, in the background of human.

AP2 alpha is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a broad spectrum of critical biological functions, including proper development of the eye, face, body wall, limbs, and neural tube. They also suppress several genes, including MCAM/MUC18, C/EBP alpha, and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, it stimulates PITX2 P1 promoter transcription activation and associates with chromatin at the PITX2 P1 promoter region.

P05549

Predicted band size: 48 kDa; Observed band size: 48 kDa

affinity purified.

Non-conjugated

Primary Antibody; Mouse Monoclonal Antibody

Mouse

Human

WB: 1/500-1/2000; IF: 1/200-1/1000; FC: 1/200-1/400; ELISA: 1/10000

WB, ICC/IF, FC, ELISA

Liquid

Supplied in PBS with 0.05% sodium azide

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Purified recombinant fragment of human TFAP2A (AA: 105-211) expressed in E. Coli.