2. Others Membrane Transporter/Ion Channel Neuronal Signaling GPCR/G Protein Autophagy Apoptosis
  3. Reference Standards Calcium Channel Dopamine Receptor Autophagy Apoptosis
  4. Penfluridol (Standard)

Penfluridol (Standard)  (Synonyms: R-16341 (Standard))

Cat. No.: HY-B1077R Purity: ≥98%
Handling Instructions Technical Support

Penfluridol (Standard) is the analytical standard of Penfluridol. This product is intended for research and analytical applications. Penfluridol (R-16341) is a potent, long-acting, first-generation, oral diphenylbutylpiperidine antipsychotic agent by targeting D2-like dopamine receptor. Penfluridol effectively inhibits TNFα-induced NF-κB activation and alleviates the severity of arthritis and colitis in vivo. Penfluridol is a Ca2+-calmodulin inhibitor. Penfluridol induces apoptosis and autophagy. Penfluridol is used for chronic schizophrenia, acute psychosis, Tourette syndrome and autoimmune diseases. Penfluridol inhibites the growth of E. faecalis planktonic cells with the MIC of 7.81 µg/ml.

For research use only. We do not sell to patients.

Penfluridol (Standard) Chemical Structure

Penfluridol (Standard) Chemical Structure

CAS No. : 26864-56-2

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Description
Molecular Weight

523.97

Formula

C28H27ClF5NO
CAS No.
SMILES

OC1(C2=CC=C(Cl)C(C(F)(F)F)=C2)CCN(CCCC(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)CC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Penfluridol (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Penfluridol (Standard)26864-56-2R-16341 (Standard)Reference StandardsCalcium ChannelDopamine ReceptorAutophagyApoptosisCa2+ channelsCa channelsOraldiphenylbutylpiperidineantipsychoticD2TNFαNF-κBarthritiscolitisspleen naive CD4+TTH1TH17M1 macrophagechronic schizophreniaacute psychosisTourette syndromeautoimmuneE. faecalisplanktonicInhibitorinhibitorinhibit

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