2. NF-κB
  3. NF-κB
  4. JSH-23 (Standard)

JSH-23 (Standard) is the analytical standard of JSH-23. This product is intended for research and analytical applications. JSH-23 is an NF-κB inhibitor which inhibits NF-κB transcriptional activity with an IC50 of 7.1 μM in lipopolysaccharide (LPS)-stimulated macrophages RAW 264.7. JSH-23 inhibits nuclear translocation of NF-κB p65 without affecting IκBα degradation.

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JSH-23 (Standard) Chemical Structure

JSH-23 (Standard) Chemical Structure

CAS No. : 749886-87-1

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Description

JSH-23 (Standard) is the analytical standard of JSH-23. This product is intended for research and analytical applications. JSH-23 is an NF-κB inhibitor which inhibits NF-κB transcriptional activity with an IC50 of 7.1 μM in lipopolysaccharide (LPS)-stimulated macrophages RAW 264.7. JSH-23 inhibits nuclear translocation of NF-κB p65 without affecting IκBα degradation.

Molecular Weight

240.34

Formula

C16H20N2
CAS No.
SMILES

NC1=CC(C)=CC=C1NCCCC2=CC=CC=C2
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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JSH-23 (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JSH-23 (Standard)749886-87-1NF-κBNuclear factor-κBNuclear factor-kappaBInhibitorinhibitorinhibit

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