p63 Antibody (YA4492)

Cat. No.: HY-P84795: Data Sheet User Guide for Antibodies
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p63 Antibody (YA4492) is a mouse-derived and non-conjugated IgG1 antibody, targeting to p63a. It can be applicated for WB, IHC-P, ELISA assays, in the background of human, mouse, rat, monkey.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
Technical Parameters
Properties
Documentation

Description	p63 Antibody (YA4492) is a mouse-derived and non-conjugated IgG1 antibody, targeting to p63a. It can be applicated for WB, IHC-P, ELISA assays, in the background of human, mouse, rat, monkey.
Background	p40/p63 functions as a sequence-specific DNA-binding transcriptional activator or repressor. Its isoforms contain varying transactivation and auto-regulating transactivation-inhibiting domains, resulting in isoform-specific activities. Isoform 2 activates RIPK4 transcription. In response to genotoxic insults and activated oncogenes, p40/p63 may cooperate with TP73/p73 to initiate p53/TP53-dependent apoptosis. It participates in Notch signaling, likely by inducing JAG1 and JAG2 expression. p40/p63 plays a crucial role in regulating epithelial morphogenesis, where the ratio of DeltaN-type to TA*-type isoforms may govern epithelial stem cell compartment maintenance and initiation of epithelial stratification from undifferentiated embryonal ectoderm. This protein is also essential for limb formation from the apical ectodermal ridge and activates transcription of the p21 promoter.
Gene ID	8626 [NCBI]
SwissProt ID	Q9H3D4
Synonyms	P51B; KET; p63α
Molecular Weight	Predicted band size: 77 kDa; Observed band size: 77 kDa
Purity	affinity purified.
Conjugation	Non-conjugated
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Host	Mouse
Reactivity	Human, Mouse, Rat, Monkey
Dilution Ratio	WB: 1/500-1/2000; IHC: 1/200-1/1000; ELISA: 1/10000
Application	WB, IHC-P, ELISA
Appearance	Liquid
Formulation	Supplied in PBS with 0.05% sodium azide.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG1
Immunogen	Synthesized peptide of human p63α.
Documentation	Data Sheet (234 KB) User Guide for Antibodies (1077 KB)

p63 Antibody (YA4492) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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p63 Antibody (YA4492)

Biological Activity

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p63 Antibody (YA4492) Related Classifications

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