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  4. Polyporaceae

Polyporaceae

 

Polyporaceae (86):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N1447
    Ganoderic acid A 81907-62-2 99.84%
    Ganoderic acid A can inhibit of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS.
    Ganoderic acid A
  • HY-N0371
    Pachymic acid 29070-92-6 99.94%
    Pachymic acid is a lanostrane-type triterpenoid from P. cocos. Pachymic acid inhibits Akt and ERK signaling pathways.
    Pachymic acid
  • HY-N1511
    Ganoderic acid D 108340-60-9 99.40%
    Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells. Ganoderic acid D induces HeLa human cervical carcinoma apoptosis.
    Ganoderic acid D
  • HY-N2995
    Poricoic acid A 137551-38-3 99.66%
    Poricoic acid A can be isolated from Poria cocos. Poricoic acid A is an orally active anti-tumor agent. Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis. Poricoic acid A also attenuatea fibroblast activation and abnormal extracellular matrix remodeling in renal fibrosis by activating AMPK and inhibiting Smad3. Poricoic acid A significantly reduces the magnitude of rise in serum creatinine and urea levels in rat model when combined with Melatonin. Poricoic acid A ameliorates renal fibrosis and podocyte injury by attenuating oxidative stress and inflammation through regulating NF-κB and Nrf2 in IRI rodent model in combination with Melatonin.
    Poricoic acid A
  • HY-N2499
    Dehydrotumulosic acid 6754-16-1 99.06%
    Dehydrotumulosic acid is one of the effective constituents of Poria cocos. Poria cocos, a popular Chinese medicinal herb of fungal origin, has been included in many combinations with other CM herbs for its traditionally claimed activities of inducing diuresis, excreting dampness, invigorating the spleen and tranquilizing the mind and its modern pharmacological use of modulating the immune system of the body.
    Dehydrotumulosic acid
  • HY-N1517
    Ganoderic acid C2 103773-62-2 99.72%
    Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses the potential anti-tumor bioactivity, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 is the inhibitor for aldose reductase with an IC50 of 43.8 µM.
    Ganoderic acid C2
  • HY-N6036
    Ganoderic acid F 98665-15-7 99.70%
    Ganoderic acid F is a ganoderic acid. Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium signaling, and endoplasmic reticulum stress.
    Ganoderic acid F
  • HY-120140
    Ganoderic acid DM 173075-45-1 99.75%
    Ganoderic acid DM, a natural triterpenoid isolated from Ganoderma lucidum, induces DNA damage, G1 cell cycle arrest and apoptosis in human breast cancer cells. Ganoderic acid DM as a specific inhibitor of osteoclastogenesis.
    Ganoderic acid DM
  • HY-N4124
    Poricoic acid B 137551-39-4
    Poricoic acid B, isolated from Poria cocos, possesses anti-tumor activity.
    Poricoic acid B
  • HY-N9366
    Tumulosic acid 508-24-7 98.66%
    Tumulosic acid, a triterpenoid, inhibits KLK5 protease activity (IC50= 14.84 μM). Tumulosic acid suppresses the proteolytic processing of LL-37 in keratinocytes at ≤10 μM.
    Tumulosic acid
  • HY-N2991
    Dehydropachymic acid 77012-31-8 99.95%
    Dehydropachymic acid is one of the major triterpenes isolated from Poria cocos. Dehydropachymic acid is more effective in autophagy-lysosome pathway (ALP) impaired cells rather than normal cells.
    Dehydropachymic acid
  • HY-N2458
    Ganoderic acid G 98665-22-6 99.10%
    Ganoderic acid G is a triterpene isolated from the surface part of gills of Ganoderma lucidum.
    Ganoderic acid G
  • HY-N1513
    Ganoderic acid H 98665-19-1 99.68%
    Ganoderic acid H is a lanostane-type triterpene isolated from Ganoderma lucidum. Ganoderic acid H suppresses growth and invasive behavior of breast cancer cells through the inhibition of transcription factors AP-1 and NF-kappaB signaling.
    Ganoderic acid H
  • HY-N1506
    Ganodermanontriol 106518-63-2
    Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity.
    Ganodermanontriol
  • HY-125437
    3-Epidehydrotumulosic acid 167775-54-4 98.14%
    3-Epidehydrotumulosic acid has inhibitory activity against AAPH-induced lysis of red blood cells.
    3-Epidehydrotumulosic acid
  • HY-125713
    Ganoderic acid Y 86377-52-8 99.32%
    Ganoderic acid Y is a α-glucosidase inhibitor with an IC50 of 170 μM for yeast α-glucosidase. Ganoderic acid Y inhibits enterovirus 71 (EV71) replication through blocking EV71 uncoating.
    Ganoderic acid Y
  • HY-N2461
    Ganoderic acid C6 105742-76-5 99.40%
    Ganoderic acid C6 has aldose reductase inhibitory activity.
    Ganoderic acid C6
  • HY-N2999
    Ganoderic acid I 98665-20-4 99.14%
    Ganoderic acid I is a triterpenoid found in ganoderma lucidum.
    Ganoderic acid I
  • HY-N3500
    Ganoderic acid D2 97653-94-6 99.69%
    Ganoderic acid D2 (compound 27) is a triterpenoid isolated from Ganoderma lucidum. Ganoderic acid D2 has anticancer, anti-inflammatory and antioxidative activity.
    Ganoderic acid D2
  • HY-N6862
    Lucideric acid A 95311-94-7 98.44%
    Lucideric acid A is a natural compound isolated from Ganoderma lucidum, inhibits PMA-induced MMP-9 activity, with anti-invasive effect on hepatoma cells.
    Lucideric acid A