Varenicline dihydrochloride (Standard) (Synonyms: CP 526555 dihydrochloride (Standard))

Cat. No.: HY-10019AR Purity: ≥98%: FAQs
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Varenicline (dihydrochloride) (Standard) is the analytical standard of Varenicline (dihydrochloride). This product is intended for research and analytical applications. Varenicline (CP 526555-18) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation[1][2][3][4][5].

For research use only. We do not sell to patients.

Varenicline dihydrochloride (Standard) Chemical Structure

CAS No. : 866823-63-4

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Description	Varenicline (dihydrochloride) (Standard) is the analytical standard of Varenicline (dihydrochloride). This product is intended for research and analytical applications. Varenicline (CP 526555-18) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation[1][2][3][4][5].
Molecular Weight	284.18
Formula	C₁₃H₁₅Cl₂N₃
CAS No.	866823-63-4
SMILES	[H]Cl.[H]Cl.C1(C2)CNCC2C3=CC4=NC=CN=C4C=C13
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Varenicline dihydrochloride (Standard) Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Varenicline dihydrochloride (Standard)866823-63-4CP 526555 dihydrochloride (Standard)nAChRNicotinic acetylcholine receptorssmoking cessationpartial agonistnicotineHUVECInhibitorinhibitorinhibit

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Varenicline dihydrochloride (Standard) (Synonyms: CP 526555 dihydrochloride (Standard))

Product Information

Purity & Documentation

Customer Review

Varenicline dihydrochloride (Standard) Related Classifications

Molarity Calculator

Dilution Calculator