2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor Adrenergic Receptor 5-HT Receptor
  4. Platelet aggregation-IN-3

Platelet aggregation-IN-3 (Compound 5) is a ligand for H2 histamine receptors, α2(A,C)-adrenergic receptors (α2-AR), and 5-HT2(B,C) serotonin receptors. Platelet aggregation-IN-3 can inhibit platelet aggregation induced by ADP and collagen and can also modulate tumour cell-induced platelet aggregation (TCIPA). Platelet aggregation-IN-3 is promising for research of antiplatelet therapy in cardiovascular diseases and the prevention of cancer-related thrombosis and tumour metastasis.

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Platelet aggregation-IN-3 Chemical Structure

Platelet aggregation-IN-3 Chemical Structure

CAS No. : 1029802-21-8

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Platelet aggregation-IN-3 Related Antibodies

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Description

Platelet aggregation-IN-3 (Compound 5) is a ligand for H2 histamine receptors, α2(A,C)-adrenergic receptors (α2-AR), and 5-HT2(B,C) serotonin receptors. Platelet aggregation-IN-3 can inhibit platelet aggregation induced by ADP and collagen and can also modulate tumour cell-induced platelet aggregation (TCIPA). Platelet aggregation-IN-3 is promising for research of antiplatelet therapy in cardiovascular diseases and the prevention of cancer-related thrombosis and tumour metastasis[1].

IC50 & Target

H2 Receptor

 

α2-adrenergic receptor

 

Histamine Receptor

 

Molecular Weight

251.76

Formula

C13H18ClN3
CAS No.
SMILES

C1(NC2=CC=C3C(CCCC3)=C2)=NCCN1.Cl
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Purity & Documentation
References
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Platelet aggregation-IN-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Platelet aggregation-IN-31029802-21-8Histamine ReceptorAdrenergic Receptor5-HT ReceptorBeta ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorH2 histamine receptorsα2-AR5-HT2(B,C) serotonin receptorscancer-related thrombosis and tumour metastasisInhibitorinhibitorinhibit

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