Undecylenoyl phenylalanine

Cat. No.: HY-135014 Purity: 95.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Undecylenoyl phenylalanine is an antagonist for α-melanocyte-stimulating hormone (MSH) and β-adrenergic receptor (β-ADR) to reduce the melanogenesis in melanocytes, reduces hyperpigmentation and thus ameliorates melasma lesions and solar lentigines.

For research use only. We do not sell to patients.

Undecylenoyl phenylalanine Chemical Structure

CAS No. : 175357-18-3

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
5 g	In-stock	Estimated Time of Arrival: December 31
10 g	In-stock	Estimated Time of Arrival: December 31
25 g	Get quote	Estimated Time of Arrival: December 31
50 g	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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α adrenergic receptor β adrenergic receptor

Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

β-adrenoceptor

Molecular Weight

331.45

Formula

C₂₀H₂₉NO₃

CAS No.

175357-18-3

Appearance

Solid

Color

White to off-white

SMILES

C=CCCCCCCCCC(N[C@H](C(O)=O)CC1=CC=CC=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 116.67 mg/mL (352.00 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.0170 mL	15.0852 mL	30.1705 mL
5 mM	0.6034 mL	3.0170 mL	6.0341 mL
10 mM	0.3017 mL	1.5085 mL	3.0170 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 95.0%

Select Batch:

Data Sheet (268 KB) SDS (393 KB)

COA (243 KB) HNMR (283 KB) MS (229 KB)

Handling Instructions (2659 KB)

References

[1]. Katoulis A, et al., A double-blind vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of melasma in females. J Cosmet Dermatol. 2014 Jun;13(2):86-90. [Content Brief]

[2]. Katoulis AC, et al., A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines. Clin Exp Dermatol. 2010 Jul;35(5):473-6. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.0170 mL	15.0852 mL	30.1705 mL	75.4262 mL
	5 mM	0.6034 mL	3.0170 mL	6.0341 mL	15.0852 mL
	10 mM	0.3017 mL	1.5085 mL	3.0170 mL	7.5426 mL
	15 mM	0.2011 mL	1.0057 mL	2.0114 mL	5.0284 mL
	20 mM	0.1509 mL	0.7543 mL	1.5085 mL	3.7713 mL
	25 mM	0.1207 mL	0.6034 mL	1.2068 mL	3.0170 mL
	30 mM	0.1006 mL	0.5028 mL	1.0057 mL	2.5142 mL
	40 mM	0.0754 mL	0.3771 mL	0.7543 mL	1.8857 mL
	50 mM	0.0603 mL	0.3017 mL	0.6034 mL	1.5085 mL
	60 mM	0.0503 mL	0.2514 mL	0.5028 mL	1.2571 mL
	80 mM	0.0377 mL	0.1886 mL	0.3771 mL	0.9428 mL
	100 mM	0.0302 mL	0.1509 mL	0.3017 mL	0.7543 mL