2. Immunology/Inflammation Apoptosis GPCR/G Protein
  3. STING Interleukin Related IFNAR TNF Receptor CXCR
  4. VB-85247

VB-85247 is a STING agonist. VB-85247 induces upregulation of inflammatory cytokines IFNα/β, TNFα, IL6, and CXCL10, as well as maturation and activation of dendritic cells by activating the STING pathway. VB-85247 can achieve regression of intrabladder tumors and can be used in bladder cancer research.

For research use only. We do not sell to patients.

VB-85247 Chemical Structure

VB-85247 Chemical Structure

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VB-85247 Related Antibodies

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Description

VB-85247 is a STING agonist. VB-85247 induces upregulation of inflammatory cytokines IFNα/β, TNFα, IL6, and CXCL10, as well as maturation and activation of dendritic cells by activating the STING pathway. VB-85247 can achieve regression of intrabladder tumors and can be used in bladder cancer research[1].

Molecular Weight

665.42

Formula

C17H16FN9Na2O8P2S2
SMILES

O=C1NC(N)=NC2=C1N=CN2[C@H]3[C@H](O4)[C@H](F)[C@@H](COP(OCCC5=NC6=C(C=NC=N6)N5OP4(S[Na])=O)(S[Na])=O)O3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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VB-85247 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VB-85247VB85247VB 85247STINGInterleukin RelatedIFNARTNF ReceptorCXCRStimulator of Interferon GenesTMEM173MITAERISMPYSILInterferon-α/β receptorInterferon-alpha/beta receptor Tumor Necrosis Factor ReceptorTNFRCXC chemokine receptorsC-X-C motif chemokine receptorsInhibitorinhibitorinhibit

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