2. Others Neuronal Signaling GPCR/G Protein
  3. Adrenergic Receptor 5-HT Receptor Isotope-Labeled Compounds
  4. Arotinolol-d5 hydrochloride

Arotinolol-d5 (hydrochloride) is deuterium labeled Arotinolol. Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand 125I-ICYP to 5HT1B-serotonergic receptor sites. Arotinolol is an antihypertensive agent for the treatment of a variety of cardiovascular pathologies as well as non-cardiovascular diseases.

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Arotinolol-d<sub>5</sub> hydrochloride Chemical Structure

Arotinolol-d5 hydrochloride Chemical Structure

CAS No. : 2514848-16-7

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Based on 1 publication(s) in Google Scholar

Other Forms of Arotinolol-d5 hydrochloride:

Arotinolol-d5 hydrochloride Related Antibodies

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α adrenergic receptor β adrenergic receptor

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5-HT Receptor 5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor

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Description

Arotinolol-d5 (hydrochloride) is deuterium labeled Arotinolol. Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker[1][2][3]. Arotinolol also shows potency for inhibiting the binding of the radioligand 125I-ICYP to 5HT1B-serotonergic receptor sites. Arotinolol is an antihypertensive agent for the treatment of a variety of cardiovascular pathologies as well as non-cardiovascular diseases[1][2][3].

IC50 & Target

5-HT1B Receptor

 

Molecular Weight

413.03

Formula

C15H17D5ClN3O2S3
CAS No.
Unlabeled CAS
SMILES

O=C(C1=CC=C(S1)C2=CSC(SC([2H])(C([2H])(C([2H])(NC(C)(C)C)[2H])O)[2H])=N2)N.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (302.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4211 mL 12.1057 mL 24.2113 mL
5 mM 0.4842 mL 2.4211 mL 4.8423 mL
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Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4211 mL 12.1057 mL 24.2113 mL 60.5283 mL
5 mM 0.4842 mL 2.4211 mL 4.8423 mL 12.1057 mL
10 mM 0.2421 mL 1.2106 mL 2.4211 mL 6.0528 mL
15 mM 0.1614 mL 0.8070 mL 1.6141 mL 4.0352 mL
20 mM 0.1211 mL 0.6053 mL 1.2106 mL 3.0264 mL
25 mM 0.0968 mL 0.4842 mL 0.9685 mL 2.4211 mL
30 mM 0.0807 mL 0.4035 mL 0.8070 mL 2.0176 mL
40 mM 0.0605 mL 0.3026 mL 0.6053 mL 1.5132 mL
50 mM 0.0484 mL 0.2421 mL 0.4842 mL 1.2106 mL
60 mM 0.0404 mL 0.2018 mL 0.4035 mL 1.0088 mL
80 mM 0.0303 mL 0.1513 mL 0.3026 mL 0.7566 mL
100 mM 0.0242 mL 0.1211 mL 0.2421 mL 0.6053 mL
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Arotinolol-d5 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Arotinolol-d52514848-16-7Adrenergic Receptor5-HT ReceptorIsotope-Labeled CompoundsBeta ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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