2. Protein Tyrosine Kinase/RTK Apoptosis
  3. PDGFR c-Kit FLT3 Apoptosis
  4. Tyrphostin AG1296 (Standard)

Tyrphostin AG1296 (Standard) 

Cat. No.: HY-13894R Purity: ≥98%
Handling Instructions Technical Support

Tyrphostin AG1296 (Standard) is the analytical standard of Tyrphostin AG1296. This product is intended for research and analytical applications. Tyrphostin AG1296 is a potent and selective inhibitor of platelet-derived growth factor receptor (PDGFR), with an IC50 of 0.8 μM. Tyrphostin AG1296 inhibits signaling of human PDGF α- and β-receptors as well as of the related stem cell factor receptor (c-Kit). Tyrphostin AG1296 is also a potent inhibitor of FLT3, with an IC50 in the micromolar range.

For research use only. We do not sell to patients.

Tyrphostin AG1296 (Standard) Chemical Structure

Tyrphostin AG1296 (Standard) Chemical Structure

CAS No. : 146535-11-7

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Description
Molecular Weight

266.29

Formula

C16H14N2O2
CAS No.
SMILES

COC1=C(OC)C=C2N=CC(C3=CC=CC=C3)=NC2=C1
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Tyrphostin AG1296 (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tyrphostin AG1296 (Standard)146535-11-7PDGFRc-KitFLT3ApoptosisPlatelet-derived growth factor receptorSCFRCD117Cluster of differentiation antigen 135CD135Fms like tyrosine kinase 3platelet-derivedgrowthfactorPDGFαβstemcellInhibitorinhibitorinhibit

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