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Results for "

M<sup>pro</sup>

" in MedChemExpress (MCE) Product Catalog:

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Click Chemistry:	ADC Synthesis (1) Labeling and Fluorescence Imaging (1) TCO (1) DBCO (6) PROTAC Synthesis (41) Azide (50) Alkynes (35)
Oligonucleotides:	miRNA mimics (4) A (8) G (4) Flavoring Agents (1) Phospholipids (2) mRNA (2) Cap Analogs (32) Antisense Oligonucleotides (3) siRNAs (42) pH Modifiers (1) Pegylated Lipids (6) U (4) Cationic Lipids (3) Mouse Pre-designed siRNA Sets (11) Adjuvant (7) Human Pre-designed siRNA Sets (20) Polymers (11) Nucleosides and their Analogs (13) miRNA antagomirs (4) Nucleoside Phosphoramidites (1) Rat Pre-designed siRNA Sets (11) miRNA inhibitors (4) Cholesterol (1) Nucleotides and their Analogs (2) miRNA agomirs (4) MicroRNAs (16) Aptamers (6) CpG ODNs (4)

6922

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

138

Biochemical Assay Reagents

2588

Peptides

MCE Kits

Inhibitory Antibodies

540

Natural
Products

616

Recombinant Proteins

1432

Isotope-Labeled Compounds

230

Antibodies

Click Chemistry

152

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15306S

Eltrombopag-13C4 1 Publications Verification SB-497115-<sup>13sup>C₄	Thrombopoietin Receptor Bacterial Apoptosis	Infection Cardiovascular Disease Cancer
Eltrombopag- ¹³C₄ (SB-497115- ¹³C₄) is ^{13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .}

HY-126906

Milbemycin A4	Antibiotic P-glycoprotein	Cancer
Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity ^[1]sup>[2].

HY-P4583

*Suc-Val-Pro-Phe-SBzl*	Cathepsin	Others
Suc-Val-Pro-Phe-SBzl (succinyl-valine-proline-phenylalanine thiobenzyl ester) is an inhibitor of CatG enzymes with IC₅₀ values of 111-225 mM.

HY-N12231

Carbazomycin B	Antibiotic Bacterial Lipoxygenase	Infection Cancer
Carbazomycin B is a bacterial metabolite and can be isolated from Streptomyces. Carbazomycin B is an antifungal and antibacterial agent. Carbazomycin B inhibits 5-lipoxygenase (5-LO) activity in extract from RBL-1 cell with the IC₅₀ Of 1.5 µM ^[1]sup>[2]sup>[3]sup>[4].

HY-B0141S7

rel-Estradiol-13C6	Isotope-Labeled Compounds	Others
rel-Estradiol- ¹³C₆ is the sup>13C-labeled rel-Estradiol .

HY-N8824

Maackiaflavanone	Others	Others
Maackiaflavanone (compound 4) is a kind of prenylated flavanone. Maackia can be isolated from M. amurensi.

HY-157926

Nitroso-PSAP	Biochemical Assay Reagents	Others
Nitroso-PSAP is a sensitive and specific chromogenic reagent for iron (Fe ²⁺), which is used for the colorimetric determination of iron in blood after mineralization with periodic acid. TNitroso-PSAP chelates with iron (Fe ²⁺) to produce a green complex (λmax=756 nm, Epsilon = 4.5 x 10 < sup > 4 < / sup > dm < sup > 3 < / sup > mol < sup > 1 < / sup > cm < sup > 1 < / sup >) .

HY-Y0589S

m-Cyanobenzoic acid-13C6 3-Carboxybenzonitrile-<sup>13sup>C₆; 3-Cyanobenzoic acid-<sup>13sup>C₆; m-Carboxybenzonitrile-<sup>13sup>C₆	Isotope-Labeled Compounds	Others
m-Cyanobenzoic acid- ¹³C₆ is the ¹³C labeled m-Cyanobenzoic acid .

HY-108166

Hydroxystilbamidine	Fluorescent Dye	Inflammation/Immunology
Hydroxystilbamidine, a dye capable of binding to both DNA and RNA, is a powerful inhibitor of cellular ribonucleases. Hydroxystilbamidine is a retrograde fluorescent tracer and a histochemical stain ^{[1]sup .}

HY-145128

GR103545	Opioid Receptor	Neurological Disease
GR103545 is a potent and selective agonist of the κ-opioid receptor (κ-OR). ¹¹GR103545 is a radiotracer for imaging κ-OR in vivo ^{[1]sup .}

HY-W011509

CyPPA	Potassium Channel	Neurological Disease
CyPPA is a positive modulator of hSK3 and hSK2, with EC₅₀ values of 14 μM and 5.6 μM, repectively. CyPPA is inactive on both hSK1 and hIK channels ^{[1]sup .}

HY-N11122

7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol	Others	Others
7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol is a cuminol glycoside. 7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol can be isolated from Rhodiola rosea sup>[1].

HY-161119

Drpitor1a	Dynamin Reactive Oxygen Species (ROS)	Cardiovascular Disease Cancer
Drpitor1a is a potent Drp1 inhibitor. Drpitor1a inhibits mitochondrial ROS production, preventes mitochondrial fission, and improves right ventricular diastolic dysfunction during IR (ischemia reperfusion) injury. Drpitor1a has the potential for the research of lung cancer ^{[1]sup .}

HY-126906R

Milbemycin A4 (Standard)	Reference Standards Antibiotic P-glycoprotein	Cancer
Milbemycin A4 (Standard) is the analytical standard of Milbemycin A4. This product is intended for research and analytical applications. Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity ^[1]sup> .

HY-16637S2

(Rac)-Folic acid-13C5,15N (Rac)-Vitamin B9-<sup>13sup>C₅,<sup>15sup>N; (Rac)-Vitamin M-<sup>13sup>C₅,<sup>15sup>N	Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite	Cancer
(Rac)-Folic acid- ¹³C₅, ¹⁵N is the ¹³C-labeled and ¹⁵N-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-16637S3

Folic acid-13C5 Vitamin B9-<sup>13sup>C₅; Vitamin M-<sup>13sup>C₅	Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite	Cancer
Folic acid- ¹³C₅ is the ¹³C-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-N7012

7,3',4'-Tri-O-methylluteolin 1 Publications Verification 5-Hydroxy-3',4',7-trimethoxyflavone	Lipoxygenase TNF Receptor Interleukin Related COX Fungal Parasite Apoptosis	Infection Inflammation/Immunology Cancer
7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) is a flavonoid with multiple biological activities. 7,3',4'-Tri-O-methylluteolin inhibits soybean lipoxygenase (LOX), with an IC₅₀ value of 23.97 µg/mL. 7,3',4'-Tri-O-methylluteolin possesses anti-inflammatory effects in Lipopolysaccharides (HY-D1056) (LPS)-induced RAW 264.7 macrophages. 7,3',4'-Tri-O-methylluteolin inhibits the binding of MDM2 with p53 and induces apoptosis in MCF-7 breast cancer cells. 7,3',4'-Tri-O-methylluteolin also has antioxidant, antifungal and antitrypanosomal activities ^[3]sup>[4]sup>[5].

HY-12741

LDN-212320 5+ Cited Publications LDN-0212320; OSU-0212320	EAAT	Neurological Disease
LDN-212320 (LDN-0212320) is a glutamate transporter (GLT-1)/excitatory amino acid transporter 2 (EAAT2) activator (at translational level). LDN-212320 (LDN-0212320) prevents nociceptive pain by upregulating astroglial GLT-1 expression in the hippocampus and ACC ^{[1]sup .}

HY-W855075A

Methyl coenzyme M ammonium	Biochemical Assay Reagents	Others
Methyl-coenzyme M can reversibly synthesize methane in methanogenic, ANME-1 and ANME-2 archaea under the catalysis of methyl-coenzyme M Reductase .

HY-B0271S1

Pyrazinamide-13C,15N Pyrazinecarboxamide-<sup>13sup>C,<sup>15sup>N; Pyrazinoic acid amide-<sup>13sup>C,<sup>15sup>N	Autophagy Antibiotic Bacterial Isotope-Labeled Compounds	Infection
Pyrazinamide- ¹³C, ¹⁵N is ¹⁵N and ¹³C labeled Pyrazinamide (HY-B0271). Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis.

HY-116881

SCH 57790	mAChR	Neurological Disease
SCH 57790 is a selective antegonist for muscarinic M2 receptor, which increases acetylcholine release, and thus improves cognitive performance. SCH 57790 reverses Scopolamine (HY-N0296)-induced memory deficits in mice, without significant toxicity (100 mg/kg).

HY-Y0850U

PVA (Mw 31000, 87-89% hydrolyzed, ~630 polymerization) Polyvinyl alcohol (Mw 31000, 87-89% hydrolyzed, ~630 polymerization); Poly(Ethenol) (Mw 31000, 87-89% hydrolyzed, ~630 polymerization)	Biochemical Assay Reagents	Others
PVA (Mw 31000, 87-89% hydrolyzed, ~630 polymerization) (Polyvinyl alcohol (Mw 31000, 87-89% hydrolyzed, ~630 polymerization); Poly(Ethenol) (Mw 31000, 87-89% hydrolyzed, ~630 polymerization)) is a biocompatible, biodegradable, nontoxic and hydrophilic synthetic polymer. PVA (Mw 31000, 87-89% hydrolyzed, ~630 polymerization) can be used to produce bone tissue engineering scaffold ^{[1]sup .}

HY-W751444

2,4-Dimethylanisole-13C6 4-Methoxy-m-xylene-<sup>13sup>C₆	Isotope-Labeled Compounds	Others
2,4-Dimethylanisole- ¹³C₆ (4-Methoxy-m-xylene- ¹³C₆) is the ¹³C-labeled 2,4-Dimethylanisole (HY-W100677).

HY-165686

Benalaxyl metabolite M2-13C3 N-(Carboxyacetyl)-N-(2,6-dimethylphenyl)-DL-alanine-<sup>13sup>C₃	Isotope-Labeled Compounds	Others
Benalaxyl metabolite M2- ¹³C₃ (N-(Carboxyacetyl)-N-(2,6-dimethylphenyl)-DL-alanine- ¹³C₃) is ¹³C labeled Benalaxyl metabolite M2 .

HY-17405S

Alarelin-(Leu-13C6,15N) TFA	Isotope-Labeled Compounds	Others
Alarelin-(Leu-sup>13C₁₀, ¹⁵N) TFA is the ¹³C- and ¹⁵N-labeled Alarelin TFA.

HY-P1130

M871 Galanin-(2-13)-Glu-His-(pro)3-(Ala-Leu)2-Ala-amide	Neuropeptide Y Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology Endocrinology Cancer
M871 (Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide) is an orally active and selective galanin receptor type 2 (GalR2) antagonist. M871 exhibits K_i values of 13.1 nM, 420 nM and >10 μM for GalR2, GalR1 and GalR3 respectively. M871 relieves the mice allergic rhinitis by reducing IgE production, as well as the number of B cells in tissues. M871 can inhibit the nerve invasion of salivary adenoid cystic carcinoma (SACC) and alleviate myocardial ischemia-reperfusion injury. M871 can be used for research on GalR2-related diseases (such as epilepsy, pain) .

HY-B0617S2

S-Adenosyl-L-methionine-13C dihydrochloride S-Adenosyl methionine-<sup>13sup>C dihydrochloride; Ademetionine-<sup>13sup>C hydrochloride; AdoMet-<sup>13sup>C dihydrochloride	Isotope-Labeled Compounds Endogenous Metabolite Apoptosis	Neurological Disease Inflammation/Immunology Cancer
S-Adenosyl-L-methionine- ¹³C (S-Adenosyl methionine- ¹³C) dihydrochloride is the ¹³C labeled S-Adenosyl-L-methionine (HY-B0617). S-Adenosyl-L-methionine (S-Adenosyl methionine) is an orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine has the potential for, cancer, liver disease and osteoarthritis research .

HY-W653853

Ritonavir-13C3 ABT 538-<sup>13sup>C₃; RTV-<sup>13sup>C₃	Isotope-Labeled Compounds Apoptosis SARS-CoV HIV Protease HIV	Cancer
Ritonavir- ¹³C₃ is ¹³C labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CL ^pro inhibitor with an IC₅₀ of 1.61 μM .

HY-Y0721S

3-Bromofluorobenzene-13C6 m-Bromofluorobenzene-<sup>13sup>C₆; m-Fluorobromobenzene-<sup>13sup>C₆; m-Fluorophenyl bromide-<sup>13sup>C₆	Isotope-Labeled Compounds	Others
3-Bromofluorobenzene- ¹³C₆ is the ¹³C labeled 3-Bromofluorobenzene .

HY-P4593

*Z-Gly-Pro-Arg-4MβNA*	Thrombin	Others
Z-Gly-Pro-Arg-4MβNA is the cleavage of the substrate of thrombin to release free 4-methoxy-2-naphthylamine (4MβNA). Free 4MβNA can be captured by 5-nitrosalicylaldehyde to produce an insoluble yellow fluorescent and marks the site of thrombin activity .

HY-B0689S1

Indinavir-13C4,15N MK-639 free base-<sup>13sup>C₄,<sup>15sup>N; L-735524 free base-<sup>13sup>C₄,<sup>15sup>N	Isotope-Labeled Compounds Apoptosis MMP HIV SARS-CoV HIV Protease	Inflammation/Immunology Cancer
Indinavir- ¹³C₄, ¹⁵N (MK-639 (free base)- ¹³C₄, ¹⁵N) is ¹³C and ¹⁵N labeled Indinavir. Indinavir (MK-639 free base) is an orally active and selective HIV-1 protease inhibitor with a K_i of 0.54 nM for PR. Indinavir exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir is also a SARS-CoV 3CL ^pro inhibitor .

HY-P4846

*Ac-Pro-Gly-Pro-OH*	CXCR	Inflammation/Immunology
Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and can be used as CXCR2 agonist. Ac-Pro-Gly-Pro-OH elicits bactericidal activity and inhibits lung inflammation, reducing immune cell apoptosis. Ac-Pro-Gly-Pro-OH enhances the production of type 1 cytokines (IFN-γ and IL-12) but inhibits the production of proinflammatory cytokines. Ac-Pro-Gly-Pro-OH has the potential for the research of sepsis .

HY-15772S1

Osimertinib-13C,d3 AZD-9291-<sup>13sup>C,d₃; Mereletinib-<sup>13sup>C,d₃	EGFR	Cancer
Osimertinib- ¹³C,d₃ is the deuterium and ¹³C labeled Osimertinib. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively.

HY-P4486

*H-Pro-Gly-Pro-OH*	Drug Derivative	Others
H-Pro-Gly-Pro-OH is a collagen-derived matrikine that has classically been described as a neutrophil chemoattractant. H-Pro-Gly-Pro-OH is perfectly positioned to focus neutrophils on the site required and direct a localized repair response. H-Pro-Gly-Pro-OH activates the transcription of neurotrophins and their receptor genes after cerebral ischemia .

HY-A0004S

Decitabine-13C5 5-Aza-2'-deoxycytidine-<sup>13sup>C₅; 5-AZA-CdR-<sup>13sup>C₅; NSC 127716-<sup>13sup>C₅	Isotope-Labeled Compounds DNA Methyltransferase Nucleoside Antimetabolite/Analog Apoptosis	Cancer
Decitabine- ¹³C₅ (5-Aza-2'-deoxycytidine- ¹³C₅) is ¹³C labeled Decitabine. Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity .

HY-P6696S

β-CL, Ala(13C3,15N) TFA	Isotope-Labeled Compounds	Others
β-CL, Ala(sup>13C₃, ¹⁵N) TFA is the ¹³C- and ¹⁵N-labeled β-CL TFA.

HY-P2708

*H-Gly-Pro-Arg-Pro-NH2*	Integrin	Cardiovascular Disease
H-Gly-Pro-Arg-Pro-NH2 is a peptide that mimics the N-terminal Gly-Pro-Arg region in the a chain of fibrin protein. H-Gly-Pro-Arg-Pro-NH2 prevents fibrin polymerization .

HY-P4487

*H-Pro-Pro-Asp-NH2*	Biochemical Assay Reagents	Others
H-Pro-Pro-Asp-NH2 is a potent and selective catalyst for asymmetric aldol reactions. H-Pro-Pro-Asp-NH2 catalyzes aldol reactions between acetone and several aldehydes .

HY-N3872

Ethyl β-D-glucopyranoside	Others	Others
Ethyl β-D-glucopyranoside (compound 10) is a kind of phenolic compound. Ethyl β-D-glucopyranoside can be isolated from ethanolic extract of Scabiosa stellata LS.

HY-P4474

*Pz-Pro-Leu-Gly-Pro-d-Arg*	Bacterial	Infection
Pz-Pro-Leu-Gly-Pro-d-Arg is a synthetic substrate of bacterial collagenase. Pz-Pro-Leu-Gly-Pro-d-Arg can be used to test bacterial collagenase activity .

HY-P4488

*H-Pro-Pro-Gln-OH*	Dipeptidyl Peptidase	Others
H-Pro-Pro-Gln-OH is a oligopeptide with excellent dipeptidyl peptidase-IV (DPP-IV) inhibitory activity .

HY-P1840

Galanin Receptor Ligand M35	Neuropeptide Y Receptor	Neurological Disease Endocrinology
Galanin Receptor Ligand M35 is a high-affinity ligand and antagonist of galanin receptor (K_d=0.1 nM). Galanin Receptor Ligand M35 exerts a K_i values of 0.11 and 2.0 nM for human galanin receptor type 1 and 2, respectively .

HY-P10304

*Cyclo(Arg-Pro)* Cyclo(pro-Arg)	Fungal	Others
Cyclo(Arg-Pro) (Cyclo(Pro-Arg)) is an inhibitor for chitinase. Cyclo(Arg-Pro) inhibits cell separation of Saccharomyces cerevisiae, without affecting its growth. Cyclo(Arg-Pro) inhibits the morphological change of Candida albicans from yeast form to filamentous form .

HY-B1374S2

Florfenicol-13C6 SCH-25298-<sup>13sup>C₆	Isotope-Labeled Compounds Bacterial Antibiotic	Infection Inflammation/Immunology
Florfenicol- ¹³C₆ (SCH-25298- ¹³C₆) is ¹³C labeled Florfenicol. Florfenicol ((-)-Florfenicol) is an orally active broad-spectrum antibacterial antibiotic with anti-inflammatory, pro apoptotic, and immunomodulatory functions .

HY-W014531S

2,6-Dichloro-4-nitrophenol-13C6	Isotope-Labeled Compounds	Others
2,6-Dichloro-4-nitrophenol-sup>13C₆ is the ¹³C-labeled 2,6-Dichloro-4-nitrophenol.

HY-W074977S

2,6-Dibromo-4-nitrophenol-13C6	Isotope-Labeled Compounds	Others
2,6-Dibromo-4-nitrophenol-sup>13C₆ is the ¹³C-labeled 2,6-Dibromo-4-nitrophenol.

HY-N0098S2

Vanillin-13C6 p-Vanillin-<sup>13sup>C₆; m-Methoxy-p-hydroxybenzaldehyde-<sup>13sup>C₆; p-Hydroxy-m-methoxybenzaldehyde-<sup>13sup>C₆	Endogenous Metabolite	Others
Vanillin- ¹³C₆ is the ¹³C labeled Vanillin . Vanillin (p-Vanillin) is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine .

HY-P4308

*Z-Pro-Pro-aldehyde-dimethyl acetal*	Prolyl Endopeptidase (PREP)	Neurological Disease
Z-Pro-Pro-aldehyde-dimethyl acetal is a potent inhibitor of prolyl endopeptidase (PREP), a cytoplasmic serine endoprotease (IC₅₀= 12 nM). Z-Pro-Pro-aldehyde-dimethyl acetal plays an important role in cognitive dysfunction in aging and neurodegenerative diseases including Alzheimer's disease .

HY-134454

*Z-Pro-Pro-CHO*	Parasite Prolyl Endopeptidase (PREP)	Infection
Z-Pro-Pro-CHO is a prolyl oligopeptidase inhibitor (_IC50: 0.16 μM and 0.01 μM for human and Schistosoma Mansoni prolyl oligopeptidase respectively) .

HY-117275S1

Meclofenamic acid-13C6 Meclofenamate-<sup>13sup>C₆	Isotope-Labeled Compounds Gap Junction Protein Endogenous Metabolite	Inflammation/Immunology
Meclofenamic acid- ¹³C₆ is the ¹³C₆ labeled Meclofenamic acid. Meclofenamic Acid (Meclofenamate), a non-steroidal, anti-inflammatory agent, is a highly selective fat mass and obesity-associated (FTO) enzyme inhibitor. Meclofenamic Acid competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid is a non-selective gap-junction blocker.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7012

7,3',4'-Tri-O-methylluteolin 1 Publications Verification 5-Hydroxy-3',4',7-trimethoxyflavone	Structural Classification Monophenols Flavonoids Classification of Application Fields Flavones Labiatae Source classification Phenols Plants Swartzia polyphylla DC. Inflammation/Immunology Disease Research Fields	Lipoxygenase TNF Receptor Interleukin Related COX Fungal Parasite Apoptosis
7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) is a flavonoid with multiple biological activities. 7,3',4'-Tri-O-methylluteolin inhibits soybean lipoxygenase (LOX), with an IC₅₀ value of 23.97 µg/mL. 7,3',4'-Tri-O-methylluteolin possesses anti-inflammatory effects in Lipopolysaccharides (HY-D1056) (LPS)-induced RAW 264.7 macrophages. 7,3',4'-Tri-O-methylluteolin inhibits the binding of MDM2 with p53 and induces apoptosis in MCF-7 breast cancer cells. 7,3',4'-Tri-O-methylluteolin also has antioxidant, antifungal and antitrypanosomal activities ^[3]sup>[4]sup>[5].

HY-N3872

Ethyl β-D-glucopyranoside	Scabiosa stellata L. Structural Classification Natural Products Caprifoliaceae Source classification Plants	Others
Ethyl β-D-glucopyranoside (compound 10) is a kind of phenolic compound. Ethyl β-D-glucopyranoside can be isolated from ethanolic extract of Scabiosa stellata LS.

HY-N3980

Guaiol Champacol; Guaiac alcohol	Infection Structural Classification Natural Products Classification of Application Fields Source classification Distemonanthus benthamianus Baill. Plants Compositae Disease Research Fields	Autophagy RAD51
Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC₅₀ of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions ^{[4]sup .}

HY-N12231

Carbazomycin B	Structural Classification Monophenols Microorganisms Source classification Phenols	Antibiotic Bacterial Lipoxygenase
Carbazomycin B is a bacterial metabolite and can be isolated from Streptomyces. Carbazomycin B is an antifungal and antibacterial agent. Carbazomycin B inhibits 5-lipoxygenase (5-LO) activity in extract from RBL-1 cell with the IC₅₀ Of 1.5 µM ^[1]sup>[2]sup>[3]sup>[4].

HY-N8824

Maackiaflavanone	Structural Classification Flavonoids Leguminosae Flavonones Source classification Maackia amurensis Rupr. et Maxim. Plants	Others
Maackiaflavanone (compound 4) is a kind of prenylated flavanone. Maackia can be isolated from M. amurensi.

HY-N11122

7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol	Structural Classification Natural Products Rhodiola rosea Linn. Source classification Crassulaceae Plants	Others
7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol is a cuminol glycoside. 7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol can be isolated from Rhodiola rosea sup>[1].

HY-N8859

Isoiridogermanal 16-Hydroxyiridal	Structural Classification Natural Products Source classification Lridaceae Plants	Others
Isoiridogermanal can be isolated from the extract of rhizomes of Iris tectorum Maxim. Isoiridogermanal is cytotoxic with IC50 values of 11 μM and 23 μM against MCF-7 and C32 cell lines.

HY-115820

*Cyclo(Pro-Pro)*	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Others
Cyclo(Pro-Pro) is a Alkaloids product that can be isolated from From Nigrospora sp.Z18-17 .

HY-N8930

Eupatorin-5-methyl ether	Structural Classification Flavonoids Flavones Labiatae Source classification Plants Swartzia polyphylla DC.	Others
Eupatorin-5-methyl ether (TMF) can be isolated from Orthosiphon stamineus. Eupatorin-5-methyl ether is a kind of flavonoid compound. Eupatorin-5-methyl ether inhibits NO production (IC50 5.5 μM).

HY-N3980R

Guaiol (Standard) Champacol (Standard); Guaiac alcohol (Standard)	Structural Classification Natural Products Source classification Distemonanthus benthamianus Baill. Plants Compositae	Reference Standards Autophagy RAD51
Guaiol (Standard) is the analytical standard of Guaiol. This product is intended for research and analytical applications. Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions ^[3][4] .

HY-N15365

Antcin B	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Virus Protease SARS-CoV
Antcin B is a SARS-CoV-2 3-chymotrypsin-like protease (3CL Pro) inhibitor. Antcin B binds to multiple key amino acid residues of 3CL Pro(such as Leu141, Asn142, Glu166, His163, etc.) through hydrogen bonds, salt bridges, and hydrophobic interactions, thereby inhibiting the activity of 3CL Pro, blocking the cleavage process of viral polyproteins, and suppressing the replication of the SARS-CoV-2 virus in host cells. Antcin B is promising for research of COVID-19 .

HY-P1938

*Cyclo(L-Pro-L-Val)*	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Cyclo(L-Pro-L-Val) is an antimicrobial and anti-inflammatory agent. Cyclo(L-Pro-L-Val) has toxic activity against plant pathogens such as R. fascians LMG 3605, and its potency may be comparable to that of Chloramphenicol (HY-B0239). Cyclo(L-Pro-L-Val) can inhibit the phosphorylation of IKKα, IKKβ, NF-κB, etc., and the activation of iNOS and COX-2, thereby exerting anti-inflammatory activity. Cyclo(L-Pro-L-Val) can be used in the research of biopesticides in the agricultural field, as well as in the research of inflammation-related diseases .

HY-P1935

*Cyclo(Ala-Pro)*	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Biochemical Assay Reagents
Cyclo(Ala-Pro) is an anticancer agent that is toxic to cancer cells such as A549, HCT-116 and HepG2 .

HY-111174

Diprotin A 3 Publications Verification Ile-pro-Ile	Microorganisms Source classification	Dipeptidyl Peptidase
Diprotin A (Ile-Pro-Ile) is an inhibitor of dipeptidyl peptidase IV (DPP-IV) .

HY-P1936

*Cyclo(Gly-L-Pro)*	Structural Classification Alkaloids Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Source classification Plants Araliaceae	Others
Cyclo(Gly-L-Pro) is a Alkaloids product that can be isolated from the roots of Panax notoginseng (Burk.)F.H.Chen .

HY-N13347

*Cyclo(Pro-Trp)*	Structural Classification Alkaloids Microorganisms Source classification	Others
Cyclo(Pro-Trp) is a natural product .

HY-P1938R

*Cyclo(L-Pro-L-Val) (Standard)*	Structural Classification Natural Products Microorganisms Source classification	Reference Standards Bacterial
Cyclo(L-Pro-L-Val) (Standard) is the analytical standard of Cyclo(L-Pro-L-Val). This product is intended for research and analytical applications. Cyclo(L-Pro-L-Val) is a 2,5-diketopiperazine, with toxic activity against phytopathogenic microorganisms (such as R. fascians LMG 3605). Cyclo(L-Pro-L-Val) shows toxicity similar to Chloramphenicol (HY-B0239) with comparable concentration. Cyclo(L-Pro-L-Val) can also inhibit gram-positive phytopathogenic bacterium. Cyclo(L-Pro-L-Val) has potential development as biopesticide[1].

HY-101402A

*Cyclo(his-pro) TFA* Cyclo(histidyl-proline) TFA; Histidylproline diketopiperazine TFA	Structural Classification Natural Products Source classification Endogenous metabolite	NF-κB Endogenous Metabolite
Cyclo(his-pro) TFA (Cyclo(histidyl-proline) TFA) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone . Cyclo(his-pro) TFA could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) TFA can cross the brain-blood-barrier and affect diverse inflammatory and stress responses .

HY-N10185

*Cyclo(D-Ala-L-Pro)*	Microorganisms Classification of Application Fields Cyclopeptides Source classification Other Diseases Disease Research Fields	Others
Cyclo(D-Ala-L-Pro) is a cyclodipeptide .

HY-N14562

*Cyclo (D-Pro-L-Val)*	Structural Classification Natural Products Microorganisms Source classification	Glycosidase
Cyclo (D-Pro-L-Val) can inhibit β-glycosidase enzyme activity with IC₅₀ of 75 μg/mL. Cyclo (D-Pro-L-Val) has no or only weak inhibitory effect on other glycosidases .

HY-P1934A

*Cyclo(L-Phe-L-Pro)*	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields Cancer	Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-W016887R

Glycyl-L-proline (Standard) H-Gly-pro-OH (Standard)	Alkaloids Structural Classification Human Gut Microbiota Metabolites Microorganisms Pyrrole Alkaloids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
H-Gly-Pro-OH (Standard) is the analytical standard of H-Gly-Pro-OH. This product is intended for research and analytical applications. H-Gly-Pro-OH is an end product of collagen metabolism that is further cleaved by prolidase.

HY-N11615

*Cyclo(Pro-Val)*	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Others
Cyclo(Pro-Val) can be isolated from Pseudomonas fluorescens GcM5-1A and has cytotoxicity .

HY-N8743

*Cyclo(Pro-Leu)* A 65190; Cyclo-(leucyl-prolyl)	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Endogenous Metabolite
Cyclo(Pro-Leu) (A 65190) is an active metabolite. Cyclo(Pro-Leu) can be isolated from Streptomyces sp. BM8. Cyclo(Pro-Leu) can be used for the research of cancer .

HY-N10004

Fructose-proline Fru-pro	Structural Classification Nicotiana tabacum L. Ketones, Aldehydes, Acids Source classification Solanaceae Plants	Others
Fructose-proline (Fru-Pro) is a major amino acid-sugar compound in tobacco leaves .

HY-101402

*Cyclo(his-pro)* Cyclo(histidyl-proline); Histidylproline diketopiperazine	Structural Classification Natural Products Source classification Endogenous metabolite	NF-κB Endogenous Metabolite
Cyclo(his-pro) (Cyclo(histidyl-proline)) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone . Cyclo(his-pro) could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) can cross the brain-blood-barrier and affect diverse inflammatory and stress responses .

HY-P1934AR

*Cyclo(L-Phe-L-Pro) (Standard)*	Structural Classification Natural Products Microorganisms Source classification	Reference Standards Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)
Gallic acid (hydrate) (Standard) is the analytical standard of Gallic acid (hydrate). This product is intended for research and analytical applications. Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-W942561

*Cyclo(D-Val-L-Pro)*	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Others
Cyclo(D-Val-L-Pro) is a Alkaloids product that can be isolated from From Phellinus igniarius .

HY-113357

m-Coumaric acid	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant. m-Coumaric acid is a BBB-penetrant metabolite of chlorogenic acid. m-Coumaric acid stimulates the cerebral nerves in vitro. m-Coumaric acid can evoke neurite outgrowth in hippocampal neuronal cells. m-Coumaric acid can promote neuronal differentiation. m-Coumaric acid increases spontaneous locomotor activity in mice by acting on the central nervous system. m-Coumaric acid inhibits the oxidation of L-dopa by epidermis tyrosinase. m-Coumaric acid attenuates non-catalytic protein glycosylation in retinas of diabetic rats .

HY-N1529

Gomisin M1 (±)-Gomisin M1	Structural Classification Lignans Phenylpropanoids Plants Schisandraceae Schisandra chinensis (Turcz.) Baill.	HIV
Gomisin M1 ((±)-Gomisin M1) is a potent anti-HIV agent with an EC₅₀ of <0.65 μM .

HY-W011704A

Phosphoenolpyruvic acid tricyclohexylammonium salt 1 Publications Verification Phosphoenolpyruvate tricyclohexylammonium salt	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Phosphoenolpyruvic acid (Phosphoenolpyruvate) tricyclohexylammonium salt is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid tricyclohexylammonium salt is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid tricyclohexylammonium salt also exhibits cytoprotective and anti-oxidative properties .

HY-113357R

m-Coumaric acid (Standard)	Structural Classification Monophenols Microorganisms Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite	Reference Standards Endogenous Metabolite
m-Coumaric acid (Standard) is the analytical standard of m-Coumaric acid. This product is intended for research and analytical applications. m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant. m-Coumaric acid is a BBB-penetrant metabolite of chlorogenic acid. m-Coumaric acid stimulates the cerebral nerves in vitro. m-Coumaric acid can evoke neurite outgrowth in hippocampal neuronal cells. m-Coumaric acid can promote neuronal differentiation. m-Coumaric acid increases spontaneous locomotor activity in mice by acting on the central nervous system. m-Coumaric acid inhibits the oxidation of L-dopa by epidermis tyrosinase. m-Coumaric acid attenuates non-catalytic protein glycosylation in retinas of diabetic rats .

HY-N3963

Gomisin M2 (+)-Gomisin M2	Classification of Application Fields Neurological Disease Source classification Lignans Plants Infection Monophenols Phenols Phenylpropanoids Schisandraceae Disease Research Fields Inflammation/Immunology Schisandra chinensis (Turcz.) Baill.	HIV
Gomisin M2 ((+)-Gomisin M2) is a lignan isolated from the fruits of Schisandra rubriflora with anti-HIV activity (EC₅₀ of 2.4 μM). Gomisin M2 exhibits anti-cancer and anti-allergic activities and has the potential for Alzheimer’s disease research .

HY-122493

Illudin M	Structural Classification Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields Cancer	DNA Alkylator/Crosslinker Apoptosis
Illudin M is a cytotoxic fungal sesquiterpene that can be isolated from the culture medium of Omphalotus illudens mushrooms. Illudin M can alkylate DNA. Illudin M has anti-tumor activities .

HY-117220

Aspochalasin M	Alkaloids Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Disease Research Fields Cancer	Others
Aspochalasin M is a colorless solid. Aspochalasin M shows modest activity against HL-60 cells with an IC₅₀ of 20.0 μM. Aspochalasin M has the potential for the research of leukemic disease .

HY-130596

DC-86-M	Structural Classification Microorganisms Antibiotics Source classification Disease Research Anticancer	Antibiotic Bacterial
DC-86-M is an antibiotic, which can be isolated from Streptomyces luteogriseus. DC-86-M exhibits antibacterial activities against Bacillus subtilis, Staphylococcus aureus, Enterococcus faecalis, Vibrio anguillarum, and Proteus vulgaris, with MIC <1 μg/mL. DC-86-M exhibits antitumor activity against mouse sarcoma 180 with LD₅₀ of 25 mg/kg .

HY-P0266A

*N-Acetyl-Ser-Asp-Lys-Pro* TFA** Ac-SDKP TFA	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Animals Source classification Disease Research Fields	Angiotensin-converting Enzyme (ACE)
N-Acetyl-Ser-Asp-Lys-Pro (TFA), an endogenous tetrapeptide secreted by bone marrow, is a specific substrate for the N-terminal site of ACE.

HY-N14783

Decarestrictin M	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Endogenous Metabolite
Decarestrictin M is a decanolactone that can be isolated from penicillium strains. Decarestrictin M is an inhibitor of cholesterol biosynthesis .

HY-N2244

Hosenkoside M (+)-Hosenkoside M	Triterpenes Structural Classification Classification of Application Fields Terpenoids Impatiens balsamina Linn. Source classification Balsaminaceae Plants Inflammation/Immunology Disease Research Fields	Others
Hosenkoside M is a baccharane glycoside isolated from the seeds of impatiens balsamina.

HY-N8956

Pachysamine M	Structural Classification Alkaloids Buxaceae Other Alkaloids Source classification Pachysandra terminalis Siebold & Zucc. Plants	Others
Pachysamine M (Compound 5) is a pregnane alkaloid. Pachysamine M is isolated from naturalPachysandra terminalisSieb. et Zucc .

HY-113356

m-Tyramine	Monophenols Source classification Disease markers Phenols Endogenous metabolite Cardiovascular System Disorder	Endogenous Metabolite
m-Tyramine is an endogenous trace amine neuromodulator. m-Tyramine has effects on the adrenergic and dopaminergic receptor ^{[1, 2]}.

HY-N4251

Periplocoside M (-)-Periplocoside M	Structural Classification Natural Products Source classification Asclepiadaceae Plants Periploca sepium Bunge	Others
Periplocoside M (compound 8) is a natural product isolated from the root bark of Periploca sepium. Periplocoside M shows antitumor activity against human A-549 and HepG2 cell lines, with the IC₅₀ of 4.84 and 7.06 μM .

HY-N6833

Rebaudioside M	Structural Classification Classification of Application Fields Source classification Plants Compositae Sweeteners Food Research Trifolium hybridum L. other families Terpenoids Other Diseases Diterpenoids Disease Research Fields	Others
Rebaudioside M, a glycoside of the ent-kaurene diterpenoid aglycone, is a non-calorie sweetener isolated from Stevia rebaudiana. Rebaudioside M has antidiabetics, antihypertension, anti-inflammatory, antioxidant, anticaries and anticancer benefits. Rebaudioside M is more than 350 times sweeter than sucrose. Rebaudioside M can be used in food and beverage .

HY-N10640

Alismanol M	Triterpenes Terpenoids Alisma orinentale (Samuel.) Juz. Plants Alismataceae	FXR
Alismanol M is a farnesoid X receptor (FXR) agonist with an EC₅₀ value of 50.25 μM. Alismanol M is a protostane-type triterpenoid that can be isolated from the rhizome of Alisma orientale. Alismanol M can be used for the research of cholestasis and nonalcoholic steatohepatitis .

HY-N15513

Harzianol M	Structural Classification Microorganisms Terpenoids Source classification Diterpenoids	NO Synthase
Harzianol M is found in Trichoderma sp. SCSIOW21. Harzianol M can inhibit the production of NO and exhibit anti-inflammatory activity .

HY-W016887

Glycyl-L-proline H-Gly-pro-OH	Alkaloids Structural Classification Human Gut Microbiota Metabolites Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Glycyl-L-proline (H-Gly-Pro-OH) is an end product of collagen metabolism that is further cleaved by prolidase.

HY-101402AR

*Cyclo(his-pro) TFA (Standard)* Cyclo(histidyl-proline) TFA (Standard); Histidylproline diketopiperazine TFA (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Reference Standards NF-κB Endogenous Metabolite
Cyclo(his-pro) (TFA) (Standard) is the analytical standard of Cyclo(his-pro) (TFA). This product is intended for research and analytical applications. Cyclo(his-pro) TFA (Cyclo(histidyl-proline) TFA) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone . Cyclo(his-pro) TFA could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) TFA can cross the brain-blood-barrier and affect diverse inflammatory and stress responses .

HY-N6833R

Rebaudioside M (Standard)	Structural Classification Trifolium hybridum L. other families Terpenoids Source classification Diterpenoids Plants Compositae	Reference Standards Others
Rebaudioside M (Standard) is the analytical standard of Rebaudioside M. This product is intended for research and analytical applications. Rebaudioside M, a glycoside of the ent-kaurene diterpenoid aglycone, is a non-calorie sweetener isolated from Stevia rebaudiana. Rebaudioside M is more than 350 times sweeter than sucrose .

HY-N3654

*Cyclo(l-Pro-d-Leu)*	Structural Classification Microorganisms Antibiotics Source classification	Tyrosinase
Cyclo(l-Pro-d-Leu) (compound 11) is a collagenase inhibitor that can be extracted from R. atalantica and also exhibits a mild tyrosinase inhibitory effect .

HY-W062171

*Cyclo-(Pro-Gly)* Pyrrolopiperazine-2,5-dione	Natural Products other families Source classification Plants	Others
Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione), an alkaloid isolated from green algae Ulva prolifera, possesses antialgal activity against the common harmful red tide microalgae . Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione) possesses antiamnesic effects and neuroprotective actions .

Cat. No.	Product Name	Chemical Structure

HY-15306S

Eltrombopag-13C4

1 Publications Verification

Eltrombopag- ¹³C₄ (SB-497115- ¹³C₄) is ^{13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .}

HY-16637S3

Folic acid-13C5
Folic acid- ¹³C₅ is the ¹³C-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-B0617S2

S-Adenosyl-L-methionine-13C dihydrochloride

S-Adenosyl-L-methionine- ¹³C (S-Adenosyl methionine- ¹³C) dihydrochloride is the ¹³C labeled S-Adenosyl-L-methionine (HY-B0617). S-Adenosyl-L-methionine (S-Adenosyl methionine) is an orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine has the potential for, cancer, liver disease and osteoarthritis research .

HY-B0141S7

rel-Estradiol-13C6
rel-Estradiol- ¹³C₆ is the sup>13C-labeled rel-Estradiol .

HY-Y0589S

m-Cyanobenzoic acid-13C6
m-Cyanobenzoic acid- ¹³C₆ is the ¹³C labeled m-Cyanobenzoic acid .

HY-16637S2

(Rac)-Folic acid-13C5,15N
(Rac)-Folic acid- ¹³C₅, ¹⁵N is the ¹³C-labeled and ¹⁵N-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-B0271S1

Pyrazinamide-13C,15N
Pyrazinamide- ¹³C, ¹⁵N is ¹⁵N and ¹³C labeled Pyrazinamide (HY-B0271). Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis.

HY-W751444

2,4-Dimethylanisole-13C6
2,4-Dimethylanisole- ¹³C₆ (4-Methoxy-m-xylene- ¹³C₆) is the ¹³C-labeled 2,4-Dimethylanisole (HY-W100677).

HY-165686

Benalaxyl metabolite M2-13C3
Benalaxyl metabolite M2- ¹³C₃ (N-(Carboxyacetyl)-N-(2,6-dimethylphenyl)-DL-alanine- ¹³C₃) is ¹³C labeled Benalaxyl metabolite M2 .

HY-17405S

Alarelin-(Leu-13C6,15N) TFA
Alarelin-(Leu-sup>13C₁₀, ¹⁵N) TFA is the ¹³C- and ¹⁵N-labeled Alarelin TFA.

HY-W653853

Ritonavir-13C3
Ritonavir- ¹³C₃ is ¹³C labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CL ^pro inhibitor with an IC₅₀ of 1.61 μM .

HY-Y0721S

3-Bromofluorobenzene-13C6
3-Bromofluorobenzene- ¹³C₆ is the ¹³C labeled 3-Bromofluorobenzene .

HY-B0689S1

Indinavir-13C4,15N

Indinavir- ¹³C₄, ¹⁵N (MK-639 (free base)- ¹³C₄, ¹⁵N) is ¹³C and ¹⁵N labeled Indinavir. Indinavir (MK-639 free base) is an orally active and selective HIV-1 protease inhibitor with a K_i of 0.54 nM for PR. Indinavir exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir is also a SARS-CoV 3CL ^pro inhibitor .

HY-15772S1

Osimertinib-13C,d3
Osimertinib- ¹³C,d₃ is the deuterium and ¹³C labeled Osimertinib. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively.

HY-A0004S

Decitabine-13C5

Decitabine- ¹³C₅ (5-Aza-2'-deoxycytidine- ¹³C₅) is ¹³C labeled Decitabine. Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity .

HY-P6696S

β-CL, Ala(13C3,15N) TFA
β-CL, Ala(sup>13C₃, ¹⁵N) TFA is the ¹³C- and ¹⁵N-labeled β-CL TFA.

HY-B1374S2

Florfenicol-13C6
Florfenicol- ¹³C₆ (SCH-25298- ¹³C₆) is ¹³C labeled Florfenicol. Florfenicol ((-)-Florfenicol) is an orally active broad-spectrum antibacterial antibiotic with anti-inflammatory, pro apoptotic, and immunomodulatory functions .

HY-W014531S

2,6-Dichloro-4-nitrophenol-13C6
2,6-Dichloro-4-nitrophenol-sup>13C₆ is the ¹³C-labeled 2,6-Dichloro-4-nitrophenol.

HY-W074977S

2,6-Dibromo-4-nitrophenol-13C6
2,6-Dibromo-4-nitrophenol-sup>13C₆ is the ¹³C-labeled 2,6-Dibromo-4-nitrophenol.

HY-N0098S2

Vanillin-13C6
Vanillin- ¹³C₆ is the ¹³C labeled Vanillin . Vanillin (p-Vanillin) is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine .

HY-117275S1

Meclofenamic acid-13C6
Meclofenamic acid- ¹³C₆ is the ¹³C₆ labeled Meclofenamic acid. Meclofenamic Acid (Meclofenamate), a non-steroidal, anti-inflammatory agent, is a highly selective fat mass and obesity-associated (FTO) enzyme inhibitor. Meclofenamic Acid competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid is a non-selective gap-junction blocker.

HY-16637S4

Folic acid-13C5,15N
Folic acid- ¹⁵N, ¹³C₅ is the ¹³C₅ and ¹⁵N labeled Folic acid (HY-16637) .

HY-19717S

DCVC-13C3,15N
DCVC- ¹³C₃, ¹⁵N is ¹⁵N and ¹³C labeled DCVC. DCVC (S-[(1E)-1,2-Dichloroethenyl]-L-cysteine) is a bioactive metabolite of trichloroethylene (TCE). DCVC inhibits pathogen-stimulated pro-inflammatory cytokines IL-1β, IL-8, and TNF-α release from tissue cultures .

HY-17430S2

Amprenavir-13C6
Amprenavir- ¹³C₆ (VX-478- ¹³C₆) is ¹³C labeled Amprenavir. Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CL ^pro inhibitor with an IC₅₀ of 1.09 μM.

HY-N10004S

Fructose-proline-13C6
Fructose-proline- ¹³C₆ is ¹³C labeled Fructose-proline.

HY-N0098S

Vanillin-13C,d3
Vanillin- ¹³C,d₃ is the ¹³C and deuterium labeled Vanillin . Vanillin (p-Vanillin) is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine .

HY-B0688S2

Dapsone-13C12

Dapsone- ¹³C₁₂ is the ¹³C₁₂ labeled Dapsone (HY-B0688). Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-B0688S3

Dapsone-15N2

Dapsone- ¹⁵N₂ (4,4′-Diaminodiphenyl sulfone- ¹⁵N₂) is ¹⁵N labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-16637S5

Folic acid-13C6
Folic acid-13C6 is a deuterated labeled Folic acid . Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .

HY-W011683S2

2'-Deoxyadenosine monohydrate-3′-13C

2'-Deoxyadenosine monohydrate-3′- ¹³C is the ¹³C labeled 2'-Deoxyadenosine monohydrate (HY-W011683) ^{^[1] 2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer>}

HY-W699983

Imidazole-15N2

Imidazole- ¹⁵N₂ (Glyoxaline- ¹⁵N₂) is ¹⁵N labeled Imidazole. Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG₂ and PGH₂) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CL ^Pro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease .

HY-N0733S2

Glucosamine-13C,15N hydrochloride
Glucosamine- ¹³C, ¹⁵N (hydrochloride) is the ¹³C and ¹⁵N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, i

HY-N0650S6

L-Serine1-13C,15N
L-Serine1- ¹³C, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-A0061S

Trifluridine-13C,15N2
Trifluridine- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Trifluridine . Trifluridine (Trifluorothymidine;5-Trifluorothymidine;TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral agent for herpes simplex virus (HSV) infection. Trifluorothymidine also has anti-orthopoxvirus activity .

HY-13771S1

Ursodeoxycholic acid-13C

Ursodeoxycholic acid- ¹³C is the ¹³C labeled Ursodeoxycholic acid. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active .

HY-Y0418S

Dulcite-13C
Dulcite- ¹³C is the ¹³C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact .

HY-14879S2

Avibactam sodium salt-13C5
Avibactam sodium salt- ¹³C₅ (NXL-104- ¹³C₅) is ¹³C labeled Avibactam (sodium). Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and *CTX-M-15* with IC₅₀s of 8 nM and 5 nM, respectively .

HY-12530S3

Velpatasvir-13C,d3
Velpatasvir- ¹³C,d₃ (GS-5816- ¹³C,d₃) is ¹³C and deuterium labeled Velpatasvir. Velpatasvir (VEL, GS-5816) is a novel pan-genotypic hepatitis C virus (HCV) nonstructural protein 5A (NS5A) inhibitor with activity against genotype 1 (GT1) to GT6 HCV replicons. Velpatasvir is also a SARS-CoV 3CL ^pro inhibitor with an IC₅₀ of 2.16 μM .

HY-D0184S6

2'-Deoxycytidine-13C,15N3
2'-Deoxycytidine- ¹³C, ¹⁵N₃ (Deoxycytidine- ¹³C, ¹⁵N₃) is ¹³C and ¹⁵N labeled 2'-Deoxycytidine. 2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer .

HY-13458S1

Droxidopa-13C2,15N hydrochloride
Droxidopa- ¹³C₂, ¹⁵N (hydrochloride) is deuterium labeled Droxidopa. Droxidopa(L-DOPS), the mixture of Droxidopa (w/w80%) and Pharmaceutical starch (w/w20%), acts as a proagent to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline); Droxidopa(L-DOPS) is capable of crossing the protective blood-brain barrier .

HY-66005S4

Acetaminophen-13C2,15N
Acetaminophen- ¹³C₂, ¹⁵N is the ¹³C and ¹⁵N labeled Acetaminophen . Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC₅₀ of 25.8 μM;is a widely used antipyretic and analgesic agent . Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor .

HY-15236S1

PSI-6206-d1,13C,15N2
PSI-6206-d1, ¹³C, ¹⁵N₂ is ¹⁵N and ¹³C labeled PSI-6206 (HY-15236). PSI-6206 (RO 2433) is the deaminated derivative of PSI-6130, which is a potent and selective inhibitor of HCV NS5B polymerase. PSI-6206 low potently inhibits HCV replicon with EC₉₀ of >100 μM.

HY-13613S2

Dutasteride-13C,15N,d
Dutasteride- ¹³C, ¹⁵N,d is ¹⁵N and deuterated labeled Dutasteride (HY-13613). Dutasteride (GG745) is a potent inhibitor of both 5α-reductase isozymes. Dutasteride may possess off-target effects on the androgen receptor (AR) due to its structural similarity to DHT .

HY-B0389S29

D-Glucose-18O
D-Glucose- ¹⁸O is the ¹⁸O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules

HY-B0389S10

D-Glucose-13C 1 Publications Verification
D-Glucose- ¹³C is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response .

HY-Y0659S1

1,2,3,4-Hydroquinoline-13C3,15N
1,2,3,4-Hydroquinoline- ¹³C₃, ¹⁵N (1,2,3,4-Tetrahydroquinoline- ¹³C₃, ¹⁵N) is the ¹³C- and ¹⁵N-labeled 1,2,3,4-Hydroquinoline (HY-Y0659).

HY-W338294S

2'-Deoxycytidine-13C monohydrate
2'-Deoxycytidine- ¹³C (monohydrate) is the ¹³C labeled 2'-Deoxycytidine .

HY-N1480S

(-)-Fucose-13C
(-)-Fucose- ¹³C is the ¹³C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti

HY-W754370

Methyltriphenylphosphonium bromide-13C,d3
Methyltriphenylphosphonium bromide- ¹³C,d₃ (Phosphonium, methyltriphenyl-, bromide (8CI,9CI)- ¹³C,d₃) is the deuterium and ¹³C labeled Methyltriphenylphosphonium bromide (HY-Y1033).

HY-B0178AS

Guanidine-13C,15N3 hydrochloride
Guanidine- ¹³C, ¹⁵N₃ (hydrochloride)is the ¹³C-labeled and ¹⁵N-labeled Guanidine hydrochloride. Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins .

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