2. Protein Tyrosine Kinase/RTK
  3. VEGFR
  4. DOTA-TMVP1446

DOTA-TMVP1446 is a VEGFR-3 targeting peptide. DOTA-TMVP1446 labeled with 68Ga accurately detectes the status of lymph node metastasis, even in micrometastatic tumors, in the B16-F10 tumor mice model. DOTA-TMVP1446 can be used as a radiotracer for cancer-metastatic sentinel lymph nodes (m-SLN) imaging.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

DOTA-TMVP1446

DOTA-TMVP1446 Chemical Structure

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DOTA-TMVP1446 Related Antibodies

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VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

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Description

DOTA-TMVP1446 is a VEGFR-3 targeting peptide. DOTA-TMVP1446 labeled with 68Ga accurately detectes the status of lymph node metastasis, even in micrometastatic tumors, in the B16-F10 tumor mice model. DOTA-TMVP1446 can be used as a radiotracer for cancer-metastatic sentinel lymph nodes (m-SLN) imaging[1].

IC50 & Target[1]

VEGFR-3

 

Molecular Weight

1868.08

Formula

C74H134N26O28S
Sequence

DOTA-PEG4-Cys-Arg-Arg-Ala-Leu-Gly-Gly-Gly-Thr-Thr-Ser-Arg
Sequence Shortening

DOTA-PEG4-CRRALGGGTTSR
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DOTA-TMVP1446 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DOTA-TMVP1446DOTA-PEG4-TMVP1446VEGFRVascular endothelial growth factor receptorVEGFR-3Targeting peptide68GaRadiotracerCancerMicrometastatic tumorsMetastatic sentinel lymph nodesm-SLNB16-F10 tumor mice modelInhibitorinhibitorinhibit

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