1. Peptides
  2. Peptide and Derivatives
  3. Inhibitors and Substrates
  4. Angiotensin A

Angiotensin A is a renin–angiotensin system (RAS) peptide that causes a vasoconstrictive effect dependent on AT1 receptors. Angiotensin A elicits pressor and renal vasoconstrictor responses in normotensive and hypertensive rats.

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Angiotensin A

Angiotensin A Chemical Structure

CAS No. : 51833-76-2

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Description

Angiotensin A is a renin–angiotensin system (RAS) peptide that causes a vasoconstrictive effect dependent on AT1 receptors. Angiotensin A elicits pressor and renal vasoconstrictor responses in normotensive and hypertensive rats[1].

Molecular Weight

1002.17

Formula

C49H71N13O10

CAS No.
Appearance

Solid

Color

white

Sequence

Ala-Arg-Val-Tyr-Ile-His-Pro-Phe

Sequence Shortening

ARVYIHPF

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (99.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9978 mL 4.9892 mL 9.9783 mL
5 mM 0.1996 mL 0.9978 mL 1.9957 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.9978 mL 4.9892 mL 9.9783 mL 24.9459 mL
5 mM 0.1996 mL 0.9978 mL 1.9957 mL 4.9892 mL
10 mM 0.0998 mL 0.4989 mL 0.9978 mL 2.4946 mL
15 mM 0.0665 mL 0.3326 mL 0.6652 mL 1.6631 mL
20 mM 0.0499 mL 0.2495 mL 0.4989 mL 1.2473 mL
25 mM 0.0399 mL 0.1996 mL 0.3991 mL 0.9978 mL
30 mM 0.0333 mL 0.1663 mL 0.3326 mL 0.8315 mL
40 mM 0.0249 mL 0.1247 mL 0.2495 mL 0.6236 mL
50 mM 0.0200 mL 0.0998 mL 0.1996 mL 0.4989 mL
60 mM 0.0166 mL 0.0832 mL 0.1663 mL 0.4158 mL
80 mM 0.0125 mL 0.0624 mL 0.1247 mL 0.3118 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Angiotensin A
Cat. No.:
HY-110183
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