2. Protein Tyrosine Kinase/RTK
  3. Bcr-Abl
  4. Kinase modulator-1

Kinase modulator-1 (P142, MS: m/z445) is a kinase modulator. Kinase modulator-1 can inhibit Bcr-Abl activity, especially against drug-resistant mutant kinases (such as T315I Bcr-Abl). Kinase modulator-1 can be used for cancers like chronic myelogenous leukemia (CML) research.

For research use only. We do not sell to patients.

Kinase modulator-1

Kinase modulator-1 Chemical Structure

CAS No. : 927697-17-4

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Kinase modulator-1 Related Antibodies

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Description

Kinase modulator-1 (P142, MS: m/z445) is a kinase modulator. Kinase modulator-1 can inhibit Bcr-Abl activity, especially against drug-resistant mutant kinases (such as T315I Bcr-Abl). Kinase modulator-1 can be used for cancers like chronic myelogenous leukemia (CML) research[1].

Molecular Weight

444.48

Formula

C25H24N4O4
CAS No.
SMILES

O=C(NC1=C(C(N(C)C)=O)C=C(C2=CN=C3NC=C(C3=C2)C4=C(OC)C=CC=C4)C=C1)OC
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Kinase modulator-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Kinase modulator-1927697-17-4Kinase modulator1Kinase modulator 1Bcr-AblModulatorT315I Bcr-AblMV4-11 cellsTHP cellsChronic myelogenous leukemiaCMLInhibitorinhibitorinhibit

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