2. Metabolic Enzyme/Protease
  3. Pyruvate Kinase
  4. ML 083

ML083 is a member of a series of highly specific allosteric activators for the tumor-specific isoform of human pyruvate kinase (M2 isoform). ML083 affects the cooperativity of phosphoenolpyruvate (PEP) binding. ML083 can be used in the research of tumors.

For research use only. We do not sell to patients.

ML 083

ML 083 Chemical Structure

CAS No. : 562867-96-3

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Description

ML083 is a member of a series of highly specific allosteric activators for the tumor-specific isoform of human pyruvate kinase (M2 isoform). ML083 affects the cooperativity of phosphoenolpyruvate (PEP) binding. ML083 can be used in the research of tumors[1].

IC50 & Target[1]

PKM2

 

Molecular Weight

454.52

Formula

C19H22N2O7S2
CAS No.
SMILES

O=S(N1CCN(S(=O)(C2=CC=C(OCCO3)C3=C2)=O)CC1)(C4=CC=C(OC)C=C4)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ML 083 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ML 083562867-96-3BML283ML083ML-083BML 283BML-283Pyruvate KinasetumorInhibitorinhibitorinhibit

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