2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Stearoylethanolamide

Stearoylethanolamide is an endocannabinoid-like compound with pro-apoptotic activity.

For research use only. We do not sell to patients.

Stearoylethanolamide Chemical Structure

Stearoylethanolamide Chemical Structure

CAS No. : 111-57-9

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Solution
10 mM * 1 mL in DMSO In-stock
Solid
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Based on 1 publication(s) in Google Scholar

Other Forms of Stearoylethanolamide:

Stearoylethanolamide Related Antibodies

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  • Purity & Documentation

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Description

Stearoylethanolamide is an endocannabinoid-like compound with pro-apoptotic activity.

IC50 & Target

Human Endogenous Metabolite

 

Cellular Effect
Cell Line Type Value Description References
MCF7 GI50
129.5 μg/mL
Compound: 4b
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
NCI/ADR-RES GI50
157.7 μg/mL
Compound: 4b
Antiproliferative activity against human NCI/ADR-RES cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human NCI/ADR-RES cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
OVCAR-3 GI50
157.7 μg/mL
Compound: 4b
Antiproliferative activity against human OVCAR3 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human OVCAR3 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
PC-3 GI50
75.6 μg/mL
Compound: 4b
Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
U-251 GI50
116.9 μg/mL
Compound: 4b
Antiproliferative activity against human U251 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human U251 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
In Vitro

Stearoylethanolamide (SEA) is present in human, rat and mouse brain in amounts comparable with those of the endocannabinoid anandamide (arachidonoylethanolamide; AEA). Stearoylethanolamide is an endocannabinoid-like compound with pro-apoptotic activity, which is regulated by NO in a way opposite to that reported for AEA[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Stearoylethanolamide Related Antibodies
Molecular Weight

327.55

Formula

C20H41NO2
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

CCCCCCCCCCCCCCCCCC(NCCO)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Stearoylethanolamide Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Stearoylethanolamide111-57-9Endogenous MetaboliteInhibitorinhibitorinhibit

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