GFPT1 Antibody (YA4191)

GFPT1 Antibody (YA4191) is a mouse-derived and non-conjugated IgG1 antibody, targeting to GFPT1. It can be applicated for WB, ICC/IF, FC, ELISA assays, in the background of human, rat, monkey.

The GFPT1 protein exerts control over the flux of glucose into the hexosamine pathway and is likely crucial in regulating the availability of precursors necessary for both N- and O-linked glycosylation of proteins. Additionally, it plays a role in the circadian regulation of clock genes such as BMAL1 and CRY1, suggesting its involvement in modulating circadian rhythms. Moreover, GFPT1 is implicated in fine-tuning the metabolic fluctuations of cytosolic UDP-GlcNAc, particularly influencing its effects on hyaluronan synthesis during tissue remodeling. These diverse functions underscore the significance of GFPT1 in coordinating metabolic processes and cellular responses related to glycosylation, circadian rhythm, and tissue remodeling.

Q06210

Predicted band size: 79 kDa; Observed band size: 79 kDa

affinity purified.

Non-conjugated

Primary Antibody; Mouse Monoclonal Antibody

Mouse

Human, Rat, Monkey

WB: 1/500-1/2000; IF: 1/200-1/1000; FC: 1/200-1/400; ELISA: 1/10000

WB, ICC/IF, FC, ELISA

Liquid

Supplied in PBS with 0.05% sodium azide

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Purified recombinant fragment of human GFPT1 (AA: 536-681) expressed in E. Coli.