2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Calcium Channel
  4. Caloxin 1b3

Caloxin 1b3, a peptide, is a selective plasma membrane Ca2+ pump 1 (PMCA1) inhibitor. Caloxin 1b3 significantly inhibits PMCA1 Ca2+–Mg2+-ATPase in the rabbit duodenal mucosa than the PMCA4 in the human erythrocyte ghosts. Caloxin 1b3 also increases cytosolic Ca2+ concentration in endothelial cells. Caloxin 1b3 can be used for cardiovascular disorders research.

For research use only. We do not sell to patients.

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Caloxin 1b3

Caloxin 1b3 Chemical Structure

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Caloxin 1b3 Related Antibodies

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

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Description

Caloxin 1b3, a peptide, is a selective plasma membrane Ca2+ pump 1 (PMCA1) inhibitor. Caloxin 1b3 significantly inhibits PMCA1 Ca2+–Mg2+-ATPase in the rabbit duodenal mucosa than the PMCA4 in the human erythrocyte ghosts. Caloxin 1b3 also increases cytosolic Ca2+ concentration in endothelial cells. Caloxin 1b3 can be used for cardiovascular disorders research[1].

Molecular Weight

1924.29

Formula

C88H150N26O22
Sequence

Thr-Ile-Pro-Lys-Trp-Ile-Ser-Ile-Ile-Gln-Ala-Leu-Arg-Gly-Gly-Gly-Ser-Lys-NH2
Sequence Shortening

TIPKWISIIQALRGGGSK-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Caloxin 1b3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Caloxin 1b3Calcium ChannelCa2+ channelsCa channelsPeptidePlasmaMembrane Ca2+ pump 1 PMCA1Cardiovascular disordersInhibitorinhibitorinhibit

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