1. Disease Areas
  2. Blood or Cardiovascular Disease

Blood or Cardiovascular Disease

Cardiovascular disease is the leading cause of death worldwide, affecting both developed and developing nations, and is associated with significant morbidity, disability, reduced productivity, and elevated healthcare expenditures, particularly among older adults. It encompasses a broad range of conditions impacting the heart or blood vessels, including hypertension, angina, atherosclerosis, ischemic heart disease, acute myocardial infarction, heart failure, stroke, arrhythmias, valvular heart disease, and peripheral vascular disease.

Blood or Cardiovascular Disease (1):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0385
    Gomisin J 66280-25-9 99.97%
    Gomisin J is a Schisandra chinensis-derived lignan that can inhibit multiple targets such as eNOS, AMPK (LKB1, CaMKIIβ), fetuin-A, NF-κB, Nrf2/HO-1, and can pass through the blood-brain barrier. Gomisin J increases NO bioavailability by activating eNOS, regulates lipid metabolism by activating the AMPK pathway, inhibits fetuin-A and NF-κB to exert anti-inflammatory effects, and activates Nrf2/HO-1 to enhance antioxidant capacity. Gomisin J has the activities of anti-hypertension, regulating liver lipid metabolism, and reducing cerebral ischemia-reperfusion injury, and can be used for research on hypertension, non-alcoholic fatty liver disease, cerebral ischemia-reperfusion injury, etc.
    Gomisin J