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  5. LEP(116-130)(mouse)

LEP(116-130)(mouse) is a synthetic leptin peptide fragment.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

LEP(116-130)(mouse) Chemical Structure

LEP(116-130)(mouse) Chemical Structure

CAS No. : 258276-95-8

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Based on 1 publication(s) in Google Scholar

LEP(116-130)(mouse) Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE LEP(116-130)(mouse)

  • Biological Activity

  • Protocol

  • Purity & Documentation

  • References

  • Customer Review

Description

LEP(116-130)(mouse) is a synthetic leptin peptide fragment.

In Vitro

LEP-(116-130) (300 µM) is unable to inhibit AP-OB binding[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

LEP(116-130)(mouse) Related Antibodies
In Vivo

LEP-(116-130) (1 mg, i.p.) results in a reduced rate of body weight gain in the presence of increased food intake compared with vehicle-injcted control mice. LEP-(116-130) significantly reduces blood glucose levels by appr 100 mg/dL. Administration of LEP-(116-130) to wild-type (+/+) C57BLKS/J-m mice for 4 or 7 days has no effect on their ability to thermoregulate[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

1560.73

Formula

C64H109N19O24S
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2
Sequence Shortening

SCSLPQTSGLQKPES-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
Animal Administration
[1]

Blood is drawn from the tail vein of each mouse 2 h before the onset of the dark period at the beginning of the study (day 0) and after 2, 4, and 6 days of treatment with 1 mg/day i.p. LEP-(116-130). Blood glucose levels are determined with a Glucometer Elite blood glucose monitor. After 4 and 7 days of treatment with 1 mg/day i.p. LEP-(116-130), sensitivity to cold is examined by placing the mice without food or water in a cold room with an ambient temperature of 4°C. Body temperature is measured with a rectal probe every hour for 4 h.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
References
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LEP(116-130)(mouse) Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LEP(116-130)(mouse)258276-95-8OthersInhibitorinhibitorinhibit

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LEP(116-130)(mouse)
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