2. Protein Tyrosine Kinase/RTK
  3. FGFR
  4. FGFR1 V561M Recombinant Human Active Protein Kinase

FGFR1 V561M Recombinant Human Active Protein Kinase 

Cat. No.: HY-E70717
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FGFR1 has been implicated in numerous cancer types including non-small cell lung cancer (NSCLC). FGFR1 is activated upon FGF binding to its extracellular domain, resulting in protein dimerization and transautophosphorylation of the intracellular tyrosine kinase domains. FGFR1 V561M gatekeeper mutation drives Fexagratinib (AZD4547) (HY-13330) resistance through STAT3 Activation and EMT. FGFR1 V561M Recombinant Human Active Protein Kinase is a recombinant FGFR1 V561M protein that can be used to study FGFR1 V561M-related functions.

For research use only. We do not sell to patients.

FGFR1 V561M Recombinant Human Active Protein Kinase

FGFR1 V561M Recombinant Human Active Protein Kinase Chemical Structure

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FGFR1 V561M Recombinant Human Active Protein Kinase Related Antibodies

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Description

FGFR1 has been implicated in numerous cancer types including non-small cell lung cancer (NSCLC). FGFR1 is activated upon FGF binding to its extracellular domain, resulting in protein dimerization and transautophosphorylation of the intracellular tyrosine kinase domains. FGFR1 V561M gatekeeper mutation drives Fexagratinib (AZD4547) (HY-13330) resistance through STAT3 Activation and EMT. FGFR1 V561M Recombinant Human Active Protein Kinase is a recombinant FGFR1 V561M protein that can be used to study FGFR1 V561M-related functions[1].

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[FGFR1 V561M Recombinant Human Active Protein Kinase]
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FGFR1 V561M Recombinant Human Active Protein Kinase Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FGFR1 V561M Recombinant Human Active Protein KinaseFGFRFibroblast growth factor receptorInhibitorinhibitorinhibit

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