2. Enzyme
  3. Disease Research Enzymes

Disease Research Enzymes

Disease research enzymes are a type of key enzymes that study the occurrence and treatment of diseases, including common β-glucuronidase, sulfatase, etc.

Disease research enzymes are mainly used for:

• Studying the occurrence and treatment of diseases

• Drug analysis

Disease Research Enzymes (153):

Cat. No. Product Name CAS No.  
  • HY-114164
    Thrombin (MW 37kDa) 9002-04-4  
    Thrombin (MW 37kDa) is a Na+-activated, allosteric serine protease that plays opposing functional roles in blood coagulation. Thrombin recognition sequence and can be used to digest GST-tagged proteins.
  • HY-P2373
    Nattokinase, Natto fermentation 133876-92-3  
    Nattokinase, Natto fermentation is a potent fibrinolytic enzyme. Nattokinase can break down blood clots by directly hydrolyzing fibrin and plasmin substrate. Nattokinase can be used for the research of cardiovascular diseases.
  • HY-108865
    Alteplase 105857-23-6  
    Alteplase (Actilyse; Activase), a tissue plasminogen activator prepared by recombination, is a thrombolytic agent that play important roles in acute ischemic stroke, pulmonary embolism, acute myocardial infarction, and occluded catheters.
    The product size below only indicate the effective content of Alteplase. The ratio of Alteplase effective content : total content = 1:46-1:50. The actual ratio depends on the batch.)
  • HY-125859
    Peroxidase, Horseradish 9003-99-0  
    Peroxidase, Horseradish actively involves in oxidizing reactive oxygen species, innate immunity, hormone biosynthesis and pathogenesis of several diseases.
  • HY-P2803
    Beta-glucuronidase (Escherichia coli) 9001-45-0  
    Beta-glucuronidase is an important lysosomal enzyme involved in the degradation of glucuronate-containing glycosaminoglycan.
  • HY-E70558
    5α-reductase, Rat(Sprague-Dawley) Liver  
    5α-reductase, Rat(Sprague-Dawley) Liver is the enzyme responsible for the conversion of testosterone into 5-alpha dihydrotestosterone (DHT), which is a potent androgen involved in male sexual differentiation.5α-reductase enzyme family is comprised of 3 subfamilies and 5 isoenzyme members: 5αR1, 5αR2, 5αR3, GPSN2, and GPSN2L.
  • HY-114164C
    Thrombin, Pig blood 9002-04-4  
    Rabbit Thrombin is a Na+-activated, allosteric serine protease that plays opposing functional roles in blood coagulation. Thrombin recognition sequence and can be used to digest GST-tagged proteins.
  • HY-P2767
    Urease, Jack bean 9002-13-5  
    Urease, Jack bean is derived from jack bean and Catalyzes hydrolysis of urea to carbon dioxide and ammonia. Urease, Jack bean is useful in the determination of urea in body fluids.
  • HY-P2812
    Phospholipase D, Streptomyces chromofuscus 9001-87-0  
    Phospholipase D, Streptomyces chromofuscus (PLD) is an enzyme of the phospholipase superfamily, which widely exists in bacteria, yeast, plants, animals and viruses, and is often used in biochemical research. Phospholipase D can catalyze the hydrolysis of phosphodiester bonds in glycerophospholipids to produce phosphatidic acid and soluble choline. Phospholipase D is involved in a variety of disease-related processes, including diabetes, atherogenesis, obesity, tumorigenesis, immune response, and neuroendocrine function.
  • HY-108903
    Hyaluronidase (human recombinant) 37326-33-3  
    Hyaluronidase (human recombinant) (Hylenex; Vorhyaluronidase alfa; rHuPH 20) is an enzyme that catalyzes the degradation of hyaluronic acid. Hyaluronidase (human recombinant) is used to improve the absorption and dispersal of parenteral fluids, medications, and contrast media.
  • HY-P2803A
    Beta-glucuronidase (bovine liver) 9001-45-0  
    Beta-glucuronidase is an important lysosomal enzyme involved in the degradation of glucuronate-containing glycosaminoglycan.
  • HY-E70234
    Sortase A, S. aureus 9033-39-0  
    Sortase A, S. aureus (SrtA), a transpeptidase enzyme is present in many Gram-positive bacteria and helps in the recruitment of the cell surface proteins. Sortase A, S. aureus plays an important part in ligation of various molecules on the cell surfaces.
  • HY-P2822
    Phosphoglycerate kinase, yeast 9001-83-6  
    Phosphoglycerate kinase, yeast (PGK), namely phosphoglycerate kinase, is a glycolytic enzyme commonly used in biochemical research. Phosphoglycerate kinase can catalyze the reversible transfer of phosphate groups from 1,3-bisphosphoglycerate (1,3-BPG) to ADP to generate 3-phosphoglycerate (3-PG) and ATP. At the same time, it can also participate in gluconeogenesis, catalyzing the opposite reaction to produce 1,3BPGA and ADP. Phosphoglycerate kinase is involved in energy metabolism, interaction with nucleic acid, tumor progression, cell death and virus replication and other related processes.
  • HY-P2972
    Sulfatase, Helix pomatia 9068-67-1  
    Sulfatase, Helix pomatia is a type I enzyme of prokaryotes and eukaryotes. Sulfatase, Helix pomatia is a sulfatase enzyme, is often used in biochemical studies.
  • HY-108844
    Rasburicase 134774-45-1  
    Rasburicase is a recombinant form of urate oxidase that works by catalyzing the oxidation of uric acid to allantoin, which has a higher solubility. Rasburicase specifically degrades uric acid, rapidly lowers blood uric acid levels, and improves inflammation and kidney damage caused by uric acid crystal deposition. Rasburicase can effectively lower uric acid and prevent uric acid nephropathy, and is used in the study of severe hyperuricemia associated with tumor lysis syndrome (TLS) and refractory gout.
  • HY-125859A
    Myeloperoxidase, human white blood cells 9003-99-0  
    Myeloperoxidase, human white blood cells (MPO) is a peroxidase. In Myeloperoxidase, human white blood cells mediate oxidative stress by promoting the production of reactive oxygen species (ROS) and active nitrogen (RNS), regulating the polarization and inflammation-related signaling pathways of microglia and neutrophils. Myeloperoxidase, human white blood cells has antibacterial activity.
  • HY-E70227
    Cathepsin G, human neutrophils 56645-49-9  
    Cathepsin G, human neutrophils (CTSH; ACC4) a serine protease found in polymorphonuclear neutrophils (PMNs), functions in inflammation.
  • HY-108845
    Tenecteplase 191588-94-0  
    Tenecteplase (TNK-tPA) is a modified tissue plasminogen activator. Tenecteplase is a recombinant human tissue plasminogen activator (rt-PA) that has been bioengineered to produce mutations in three gene loci. Tenecteplase (TNK-tPA) can be used in the study of acute ischemic stroke.
  • HY-P2733
    Glycerol-3-phosphate oxidase, E. coli 9046-28-0  
    Glycerol-3-phosphate oxidase, E. coli (GPO) is a key intermediate in glycerol metabolism. Glycerol-3-phosphate oxidase is the skeleton of phospholipids in membrane lipids, and also a substrate in the respiratory chain. Glycerol-3-phosphate oxidase produces electrons through oxidation.
  • HY-E70452
    Microbial Transglutaminase 80146-85-6  
    Microbial Transglutaminase (MTG) is a transglutaminase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture.