2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. TD-6301

TD-6301 is a bladder-selective M2/4 muscarinic receptor antagonist. TD-6301 binds to and blocks M2/4 muscarinic receptors with high selectivity, especially human M2 receptors with strong affinity (Ki = 0.36 nM). TD-6301 inhibits volume-induced bladder contractions (ID50 = 0.075 mg/kg). TD-6301 can be used in the research of overactive bladder.

For research use only. We do not sell to patients.

TD-6301 Chemical Structure

TD-6301 Chemical Structure

CAS No. : 690999-15-6

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TD-6301 Related Antibodies

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Description

TD-6301 is a bladder-selective M2/4 muscarinic receptor antagonist. TD-6301 binds to and blocks M2/4 muscarinic receptors with high selectivity, especially human M2 receptors with strong affinity (Ki = 0.36 nM). TD-6301 inhibits volume-induced bladder contractions (ID50 = 0.075 mg/kg). TD-6301 can be used in the research of overactive bladder[1].

IC50 & Target

Ki: 0.36 nM (human M2 muscarinic receptor)
Molecular Weight

639.91

Formula

C40H57N5O2
CAS No.
SMILES

NC(C(C1=CC=CC=C1)(C2=CC=CC=C2)[C@H]3CN(CC3)CCCCCCCN(C4CCN(CC4)CC5=CN=CC=C5OC)C(C)C)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TD-6301 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TD-6301690999-15-6TD6301TD 6301mAChRMuscarinic acetylcholine receptoroveractive bladderrats.Inhibitorinhibitorinhibit

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