1. GPCR/G Protein
  2. GHSR
  3. des-​Gln14-​Ghrelin

des-Gln14-Ghrelin is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca2+]i in CHO-GHSR62 cells, with an EC50 of 2.4 nM.

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des-​Gln14-​Ghrelin Chemical Structure

des-​Gln14-​Ghrelin Chemical Structure

CAS No. : 293735-04-3

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5 mg USD 335 In-stock
10 mg USD 490 In-stock
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Description

des-Gln14-Ghrelin is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca2+]i in CHO-GHSR62 cells, with an EC50 of 2.4 nM[1].

Molecular Weight

3186.67

Formula

C142H237N43O40

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Gly-Ser-{Oct-Ser}-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg

Sequence Shortening

GS-{Oct-Ser}-FLSPEHQKAQRKESKKPPAKLQPR

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (31.38 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.3138 mL 1.5690 mL 3.1381 mL
5 mM 0.0628 mL 0.3138 mL 0.6276 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.3138 mL 1.5690 mL 3.1381 mL 7.8452 mL
5 mM 0.0628 mL 0.3138 mL 0.6276 mL 1.5690 mL
10 mM 0.0314 mL 0.1569 mL 0.3138 mL 0.7845 mL
15 mM 0.0209 mL 0.1046 mL 0.2092 mL 0.5230 mL
20 mM 0.0157 mL 0.0785 mL 0.1569 mL 0.3923 mL
25 mM 0.0126 mL 0.0628 mL 0.1255 mL 0.3138 mL
30 mM 0.0105 mL 0.0523 mL 0.1046 mL 0.2615 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
des-​Gln14-​Ghrelin
Cat. No.:
HY-P1366
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