2. Cell Cycle/DNA Damage
  3. Wee1
  4. WEE1-IN-13

WEE1-IN-13 (Compound 10) is a highly selective WEE1 kinase inhibitor (IC50=0.7 nM). WEE1-IN-13 abrogates the G2/M checkpoint and induces tumor cell apoptosis. WEE1-IN-13 is promising for research of solid tumors (e.g., non-small cell lung cancer, ovarian cancer).

For research use only. We do not sell to patients.

WEE1-IN-13

WEE1-IN-13 Chemical Structure

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WEE1-IN-13 Related Antibodies

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Description

WEE1-IN-13 (Compound 10) is a highly selective WEE1 kinase inhibitor (IC50=0.7 nM). WEE1-IN-13 abrogates the G2/M checkpoint and induces tumor cell apoptosis. WEE1-IN-13 is promising for research of solid tumors (e.g., non-small cell lung cancer, ovarian cancer)[1].

Molecular Weight

446.57

Formula

C23H26N8S
SMILES

C[C@H](C1=C(C2=C(N1C)N=C(N=C2)NC3=CN(N=C3)C4CCN(CC4)C)C#N)C5=CC=CS5
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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WEE1-IN-13 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WEE1-IN-13Wee1WEE1 kinasetumor cellsolid tumorsInhibitorinhibitorinhibit

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WEE1-IN-13
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HY-178190
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