2. Apoptosis
  3. Apoptosis
  4. Apoptosis inducer 37

Apoptosis inducer 37 (Derivative 10) is an apoptosis inducer. Apoptosis inducer 37 exerts anticancer effects by inducing S-G2/M cell cycle arrest and promoting cell apoptosis. Apoptosis inducer 37 has significant inhibitory activity against HCT116, SKOV3 and HepG2 cancer cells (IC50 values are 24.98 μM, 26.15 μM and 23.09 μM, respectively). Apoptosis inducer 37 has antitumor effects and can be used in ovarian cancer research.

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Apoptosis inducer 37 Chemical Structure

Apoptosis inducer 37 Chemical Structure

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Description

Apoptosis inducer 37 (Derivative 10) is an apoptosis inducer. Apoptosis inducer 37 exerts anticancer effects by inducing S-G2/M cell cycle arrest and promoting cell apoptosis. Apoptosis inducer 37 has significant inhibitory activity against HCT116, SKOV3 and HepG2 cancer cells (IC50 values are 24.98 μM, 26.15 μM and 23.09 μM, respectively). Apoptosis inducer 37 has antitumor effects and can be used in ovarian cancer research[1].

Molecular Weight

565.56

Formula

C27H37BrN2O4S
SMILES

[H][C@]12CC[C@@]34CC/C([C@@](CC[C@]3([C@@]1(CCC[C@@]2(C(O)=O)C)C)[H])(C4)C)=N\NS(=O)(C5=CC=C(C=C5)Br)=O
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Apoptosis inducer 37 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Apoptosis inducer 37Apoptosis inducer37Apoptosis inducer-37ApoptosisHCT116 cellsSKOV3 cellsHepG2 cellsOvarian cancerInhibitorinhibitorinhibit

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