2. Immunology/Inflammation
  3. IFNAR Interleukin Related COX
  4. BMP-4 acetate

BMP-4 acetate is a penetrating heparin-binding peptide with anti-inflammatory and anti-chondrogenic functions. BMP-4 acetate regulates the iNOS-IFN-IL6 signaling pathway to inhibit the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6, effectively suppressing inflammation and alleviating various arthritis symptoms in murine chondrocytes and macrophages.

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Custom Peptide Synthesis

BMP-4 acetate

BMP-4 acetate Chemical Structure

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Based on 1 publication(s) in Google Scholar

Other Forms of BMP-4 acetate:

BMP-4 acetate Related Antibodies

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IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22

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Description

BMP-4 acetate is a penetrating heparin-binding peptide with anti-inflammatory and anti-chondrogenic functions. BMP-4 acetate regulates the iNOS-IFN-IL6 signaling pathway to inhibit the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6, effectively suppressing inflammation and alleviating various arthritis symptoms in murine chondrocytes and macrophages[1].

IC50 & Target

IL-6

 

COX-2

 

Molecular Weight

1308.52 (free base)

Formula

C52H93N25O13S.xC2H4O2
Appearance

Crystal

Color

White to off-white

Sequence

Arg-Lys-Lys-Asn-Pro-Asn-Cys-Arg-Arg-His
Sequence Shortening

RKKNPNCRRH
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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BMP-4 acetate Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BMP-4BMP4BMP 4IFNARInterleukin RelatedCOXInterferon-α/β receptorInterferon-alpha/beta receptor ILCyclooxygenaseInhibitorinhibitorinhibit

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BMP-4 acetate
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