1. MAPK/ERK Pathway Stem Cell/Wnt JAK/STAT Signaling
  2. ERK STAT
  3. Fulipiftide

Fulipiftide  (Synonyms: PSP 29-mer, anti-inflammatory peptide)

Cat. No.: HY-P10953
Handling Instructions Technical Support

Fulipiftide is a short peptide derived from pigment epithelium-derived factor (PEDF). Fulipiftide induces the expansion of nuclear stem cell factor +TSPC by activating ERK2 and STAT3 signaling pathways. Fulipiftide has anti-inflammatory activity and can be used in the study of acute tendon injury.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Fulipiftide Chemical Structure

Fulipiftide Chemical Structure

CAS No. : 2868985-56-0

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Based on 1 publication(s) in Google Scholar

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Description

Fulipiftide is a short peptide derived from pigment epithelium-derived factor (PEDF). Fulipiftide induces the expansion of nuclear stem cell factor +TSPC by activating ERK2 and STAT3 signaling pathways. Fulipiftide has anti-inflammatory activity and can be used in the study of acute tendon injury[1][2].

IC50 & Target[2]

ERK2

 

STAT3

 

Molecular Weight

3284.59

Formula

C144H227N41O47

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Ac-Ser-Leu-Gly-Ala-Glu-Gln-Arg-Thr-Glu-Ser-Ile-Ile-His-Arg-Ala-Leu-Tyr-Tyr-Asp-Leu-Ile-Ser-Ser-Pro-Asp-Ile-His-Gly-Thr-NH2

Sequence Shortening

Ac-SLGAEQRTESIIHRALYYDLISSPDIHGT-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (15.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.3045 mL 1.5223 mL 3.0445 mL
5 mM 0.0609 mL 0.3045 mL 0.6089 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.3045 mL 1.5223 mL 3.0445 mL 7.6113 mL
5 mM 0.0609 mL 0.3045 mL 0.6089 mL 1.5223 mL
10 mM 0.0304 mL 0.1522 mL 0.3045 mL 0.7611 mL
15 mM 0.0203 mL 0.1015 mL 0.2030 mL 0.5074 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Fulipiftide
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HY-P10953
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