PCK2 Antibody (YA4318)

PCK2 Antibody (YA4318) is a mouse-derived and non-conjugated IgG1 antibody, targeting to PCK2. It can be applicated for WB, IHC-P, ICC/IF, FC, ELISA assays, in the background of human, rat, monkey.

Phosphoenolpyruvate carboxykinase 2 (PCK2) is an enzyme that plays a crucial role in glucose metabolism by catalyzing the rate-limiting step in the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP). This metabolic pathway is significant for the synthesis of glucose from lactate and other precursors derived from the citric acid cycle. PCK2's enzymatic activity contributes to gluconeogenesis, a process crucial for maintaining glucose homeostasis, especially during fasting or periods of increased energy demand. By converting OAA to PEP, PCK2 facilitates the generation of glucose, which is essential for providing energy to various tissues, including the brain and red blood cells. It has to emphasize PCK2's pivotal role in the metabolic pathway that enables the synthesis of glucose from non-carbohydrate sources, highlighting its importance in maintaining energy balance within the cell.

Q16822

Predicted band size: 71 kDa; Observed band size: 71 kDa

affinity purified.

Non-conjugated

Primary Antibody; Mouse Monoclonal Antibody

Mouse

Human, Rat, Monkey

WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FC: 1/200-1/400; ELISA: 1/10000

WB, IHC-P, ICC/IF, FC, ELISA

Liquid

Supplied in PBS with 0.05% sodium azide

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Purified recombinant fragment of human PCK2 (AA: 44-175) expressed in E. Coli.