2. Antibody-drug Conjugate/ADC Related Immunology/Inflammation Cell Cycle/DNA Damage
  3. Antibody-Drug Conjugates (ADCs) CD2 Topoisomerase
  4. M3554

M3554 is an anti-GD2 antibody-drug conjugate (ADC) based on the humanized anti-GD2 antibody. M3554 consists of the humanized monoclonal antibody Dinutuximab (HY-P9933) linked to a topoisomerase 1 inhibitor Exatecan (HY-13631) via a cleavable β-glucuronide linker. M3554 can be used for the study of neuroblastoma, osteosarcoma or glioma.

For research use only. We do not sell to patients.

M3554

M3554 Chemical Structure

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Based on 1 publication(s) in Google Scholar

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M3554 Related Antibodies

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Description

M3554 is an anti-GD2 antibody-drug conjugate (ADC) based on the humanized anti-GD2 antibody. M3554 consists of the humanized monoclonal antibody Dinutuximab (HY-P9933) linked to a topoisomerase 1 inhibitor Exatecan (HY-13631) via a cleavable β-glucuronide linker. M3554 can be used for the study of neuroblastoma, osteosarcoma or glioma[1].

Clinical Trial
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[M3554]
Shipping

Shipping with dry ice.
Storage

-80°C, protect from light
Purity & Documentation
References
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M3554 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

M3554M 3554M-3554Antibody-Drug Conjugates (ADCs)CD2TopoisomeraseAntibody-Drug ConjugatesCluster of differentiation 2Antitumor activitypositive neuroblastoma cell linesInhibitorinhibitorinhibit

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