2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. Perfluoroenanthic acid

Perfluoroenanthic acid  (Synonyms: Perfluoroheptanoic acid; Tridecafluoroheptanoic acid; PFHpA)

Cat. No.: HY-21197
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Perfluoroenanthic acid (Perfluoroheptanoic acid) is a type of perfluoroalkyl substance (PFAS) that can negatively impact the development of seminiferous tubules and m6A RNA methylation in the testes of offspring mice when exposed during pregnancy, consequently disrupting spermatogenesis and leading to reproductive toxicity. Perfluoroenanthic acid alters the morphology of dendritic spines and synaptic formation in primary cortical neuron cultures, enhancing neuronal activity and synaptic transmission, and increasing the expression of excitatory synapse-related proteins Synaptophysin and PSD95.

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Perfluoroenanthic acid Chemical Structure

Perfluoroenanthic acid Chemical Structure

CAS No. : 375-85-9

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Perfluoroenanthic acid Related Antibodies

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Description

Perfluoroenanthic acid (Perfluoroheptanoic acid) is a type of perfluoroalkyl substance (PFAS) that can negatively impact the development of seminiferous tubules and m6A RNA methylation in the testes of offspring mice when exposed during pregnancy, consequently disrupting spermatogenesis and leading to reproductive toxicity. Perfluoroenanthic acid alters the morphology of dendritic spines and synaptic formation in primary cortical neuron cultures, enhancing neuronal activity and synaptic transmission, and increasing the expression of excitatory synapse-related proteins Synaptophysin and PSD95[1][2].

Molecular Weight

364.06

Synonyms

Perfluoroheptanoic acid; Tridecafluoroheptanoic acid; PFHpA

Formula

C7HF13O2
CAS No.
SMILES

O=C(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Perfluoroenanthic acid Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Perfluoroenanthic acid375-85-9Perfluoroheptanoic acid Tridecafluoroheptanoic acid PFHpAiGluRIonotropic glutamate receptorsPerfluoroalkyl substancespregnancymouse seminiferous tubules and testesspermatogenesisdendritic spinessynapsesneural activityInhibitorinhibitorinhibit

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