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  4. Insulin icodec

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec can be used for the research of type 2 diabetes.

For research use only. We do not sell to patients.

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Insulin icodec Chemical Structure

Insulin icodec Chemical Structure

CAS No. : 1188379-43-2

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Based on 1 publication(s) in Google Scholar

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Description

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec can be used for the research of type 2 diabetes[1].

Molecular Weight

6380.26

Formula

C280H435N71O87S6

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

Sequence

Chain1:Phe-Val-Asn-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-His-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-His-Tyr-Thr-Pro-{Lys(2OEG-γGlu-C20 diacid)} Chain2:Phe-Val-Asn-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-His-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-His-Tyr-Thr-Pro-Lys Chain3:{Ggu}-{Oaa}-{Oaa}(Disulfide:Chain1 Cys7-Chain2 Cys7, Disulfide:Chain1 Cys19-Chain2 Cys20, Disulfide:Chain 2 Cys6-Cys11, Amide bridge:Chain1 Lys29 to Chain3 ω-amino acid3)

Sequence Shortening

Chain1:FVNQHLCGSHLVEALHLVCGERGFHYTP-{Lys(2OEG-γGlu-C20 diacid)}; Chain2:GIVEQCCTSICSLEQLENYCN; Chain3:{Ggu}-{Oaa}-{Oaa} (Disulfide:Chain1 Cys7-Chain2 Cys7, Disulfide:Chain1 Cys19-Chain2 Cys20, Disulfide:Chain2 Cys6-Cys11, Amide bridge:Chain1 Lys29 to Chain3 ω-amino acid3)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at 4°C, do not freeze

Purity & Documentation

Purity: 95.00%

References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Insulin icodec
Cat. No.:
HY-P4070
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