2. PROTAC Apoptosis
  3. E3 Ligase Ligand-Linker Conjugates IAP
  4. XIAP ligand-Linker Conjugate 2

XIAP ligand-Linker Conjugate 2 is an E3 ligase ligand-linker conjugate that incorporates the XIAP BIR2 ligand XB2M54 (HY-175348) and linker. XIAP ligand-Linker Conjugate 2 can be used for synthesis of PROTAC GNE-1567 (HY-175448).

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XIAP ligand-Linker Conjugate 2

XIAP ligand-Linker Conjugate 2 Chemical Structure

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XIAP ligand-Linker Conjugate 2 Related Antibodies

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Description

XIAP ligand-Linker Conjugate 2 is an E3 ligase ligand-linker conjugate that incorporates the XIAP BIR2 ligand XB2M54 (HY-175348) and linker. XIAP ligand-Linker Conjugate 2 can be used for synthesis of PROTAC GNE-1567 (HY-175448)[1].

IC50 & Target[1]

XIAP

 

Molecular Weight

738.62

Formula

C35H40BrN5O8
SMILES

OC(CCOCCOCCC(N1C2=C(N(C([C@H]([C@@H]1C)NC([C@@H](NC)C)=O)=O)CC3=C(C=CC4=C3C=CC(Br)=C4)OC)C=CC(C#N)=C2)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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XIAP ligand-Linker Conjugate 2 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

XIAP ligand-Linker Conjugate 2E3 Ligase Ligand-Linker ConjugatesIAPXIAPBIR2Inhibitorinhibitorinhibit

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XIAP ligand-Linker Conjugate 2
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