2. JAK/STAT Signaling
  3. Pim
  4. NMS-P645

NMS-P645 is a PIM1 inhibitor. NMS-P645 exhibits anti-proliferative activity when combined with GDC-0941 (HY-50094) in TMPRSS2/ERG positive and negative PCa cells. NMS-P645 can reverse PIM1-induced pro-survival signals in prostate cells. NMS-P645 can be studied in research on prostate cancer.

For research use only. We do not sell to patients.

NMS-P645

NMS-P645 Chemical Structure

CAS No. : 1482518-95-5

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NMS-P645 Related Antibodies

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Description

NMS-P645 is a PIM1 inhibitor. NMS-P645 exhibits anti-proliferative activity when combined with GDC-0941 (HY-50094) in TMPRSS2/ERG positive and negative PCa cells. NMS-P645 can reverse PIM1-induced pro-survival signals in prostate cells. NMS-P645 can be studied in research on prostate cancer[1].

Molecular Weight

512.09

Formula

C28H38ClN5O2
CAS No.
SMILES

O=C(N[C@@H](C1CCCCC1)CN2CCN(C)CC2)C[C@H]3CNC(C4=CC(C5=CC=CC(Cl)=C5)=CN43)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NMS-P645 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NMS-P6451482518-95-5PimPim kinasesInhibitorinhibitorinhibit

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HY-117744
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