2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. HSP
  4. A17 peptide

A17 peptide is a Hsp70-targeting peptide. A17 peptide binds to the ATP-binding domains of Hsp70. A17 peptide specifically inhibits the chaperone activity, thereby increasing the cells' sensitivity to apoptosis induced by chemotherapeutic agents, such as Cisplatin (HY-17394). A17 peptide can be used for anticancer chemotherapy research, such multiple myeloma.

For research use only. We do not sell to patients.

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A17 peptide

A17 peptide Chemical Structure

CAS No. : 1140483-31-3

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A17 peptide Related Antibodies

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Description

A17 peptide is a Hsp70-targeting peptide. A17 peptide binds to the ATP-binding domains of Hsp70. A17 peptide specifically inhibits the chaperone activity, thereby increasing the cells' sensitivity to apoptosis induced by chemotherapeutic agents, such as Cisplatin (HY-17394). A17 peptide can be used for anticancer chemotherapy research, such multiple myeloma[1].

IC50 & Target[1]

HSP70

 

Molecular Weight

1636.83

Formula

C76H105N19O20S
CAS No.
Sequence

Tyr-Cys-Ala-Tyr-Tyr-Ser-Pro-Arg-His-Lys-Thr-Thr-Phe
Sequence Shortening

YCAYYSPRHKTTF
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A17 peptide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

A17 peptide1140483-31-3HSPHeat shock proteinsTargeting peptideHsp70ATP-binding domainsApoptosisCisplatinB16F10 cellsAnticancer chemotherapyMultiple myelomaInhibitorinhibitorinhibit

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