FOXM1 Antibody (YA1112)

FOXM1 Antibody (YA1112) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FOXM1.

FOXM1, a crucial transcription factor, governs the expression of cell cycle genes vital for DNA replication and mitosis, underscoring its pivotal role in orchestrating cellular processes. Beyond its involvement in cell proliferation control, FOXM1 also contributes to DNA break repair, actively participating in the DNA damage checkpoint response. Notably, FOXM1 promotes the transcription of PHB2, emphasizing its diverse regulatory functions. Furthermore, FOXM1 interacts with PINT87aa, a product encoded by the circular form of the long non-coding RNA LINC-PINT, and this interaction serves to inhibit FOXM1-mediated transcription of PHB2, revealing an intricate layer of regulatory control in cellular transcriptional processes.

Q08050

Predicted band size: 84 kDa; Observed band size: 110 kDa

Affinity Purified

Non-conjugated

Unmodified

Epigenetics and Nuclear Signaling

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse

IHC-P: 1:1000; ICC: 1:100

IHC-P, ICC/IF

Human colon tissue, human colon cancer tissue, HeLa, MEF.

Liquid

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

Recombinant protein within human FOXM1 aa 1-400.