Clozapine N-oxide dihydrochloride (Standard)

Cat. No.: HY-17366AR: Handling Instructions
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Clozapine N-oxide (dihydrochloride) (Standard) is the analytical standard of Clozapine N-oxide (dihydrochloride). This product is intended for research and analytical applications. Clozapine N-oxide dihydrochloride is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide dihydrochloride activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide dihydrochloride can cross the blood-brain barrier[1][2][3][4]. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist[5][6].

For research use only. We do not sell to patients.

Clozapine N-oxide dihydrochloride (Standard) Chemical Structure

CAS No. : 2250025-93-3

Size	Stock	Quantity
5 mg	Get quote 5 - 7 weeks 4 - 6 weeks 4 - 6 weeks	Estimated Time of Arrival: December 31
10 mg	Get quote 5 - 7 weeks 4 - 6 weeks 4 - 6 weeks	Estimated Time of Arrival: December 31
25 mg	Get quote 5 - 7 weeks 4 - 6 weeks 4 - 6 weeks	Estimated Time of Arrival: December 31
50 mg	Get quote 5 - 7 weeks 4 - 6 weeks 4 - 6 weeks	Estimated Time of Arrival: December 31
100 mg	Get quote 5 - 7 weeks 4 - 6 weeks 4 - 6 weeks	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Product Information
Purity & Documentation
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Information	Clozapine N-oxide (dihydrochloride) (Standard) is the analytical standard of Clozapine N-oxide (dihydrochloride). This product is intended for research and analytical applications. Clozapine N-oxide dihydrochloride is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide dihydrochloride activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide dihydrochloride can cross the blood-brain barrier[1][2][3][4]. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist[5][6].
Application	The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight	415.74
Formula	C₁₈H₂₁Cl₃N₄O
CAS No.	2250025-93-3
SMILES	C[N+]1([O-])CCN(C2=NC3=CC(Cl)=CC=C3NC4=CC=CC=C42)CC1.[H]Cl.[H]Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)