2. PI3K/Akt/mTOR Stem Cell/Wnt MAPK/ERK Pathway
  3. GSK-3 p38 MAPK
  4. TCS 183

TCS 183, a peptide, is a GSK-3β inhibitor. TCS 183 blocks GSK-3β autoinhibition and decreases the level of AMPK phosphorylation. TCS 183 can be used for neuropathological diseases, particularly Alzheimer’s disease, research.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

TCS 183

TCS 183 Chemical Structure

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TCS 183 Related Antibodies

Top Publications Citing Use of Products

View All GSK-3 Isoform Specific Products:

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GSK-3 GSK-3α GSK-3β

View All p38 MAPK Isoform Specific Products:

View All Isoforms
p38 MAPK p38α p38β MAPK13 p38δ p38γ

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Description

TCS 183, a peptide, is a GSK-3β inhibitor. TCS 183 blocks GSK-3β autoinhibition and decreases the level of AMPK phosphorylation. TCS 183 can be used for neuropathological diseases, particularly Alzheimer’s disease, research[1].

IC50 & Target[1]

GSK-3β

 

Molecular Weight

1425.57

Formula

C58H96N20O20S
Sequence

Met-Ser-Gly-Arg-Pro-Arg-Thr-Thr-Ser-Phe-Ala-Glu-Ser-NH2
Sequence Shortening

MSGRPRTTSFAES-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TCS 183 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TCS 183TCS183TCS-183GSK-3p38 MAPKGlycogen synthase kinase-3Glycogen synthase kinase 3PeptideGSK-3βInhibitorAutoinhibitionAMPKAlzheimer’s diseaseinhibitorinhibit

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