Vaccinia virus capping enzyme

Cat. No.: HY-E70080: Data Sheet
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Vaccinia virus capping enzyme is a transcription initiation factor. Vaccinia virus capping enzyme is a heterodimer of D1 (844 aa) and D12 (287 aa) polypeptides that executes all three steps in m7GpppRNA synthesis. Vaccinia virus capping enzyme has been used widely as a reagent for capping and cap-labeling RNAs in vitro.

For research use only. We do not sell to patients.

Vaccinia virus capping enzyme Chemical Structure

Size	Price	Stock	Quantity
500 U		In-stock	Estimated Time of Arrival: December 31
1 KU		In-stock	Estimated Time of Arrival: December 31

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Based on 1 publication(s) in Google Scholar

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Description	Vaccinia virus capping enzyme is a transcription initiation factor. Vaccinia virus capping enzyme is a heterodimer of D1 (844 aa) and D12 (287 aa) polypeptides that executes all three steps in m7GpppRNA synthesis. Vaccinia virus capping enzyme has been used widely as a reagent for capping and cap-labeling RNAs in vitro^[1]^[2].
In Vitro	Vaccinia virus capping enzyme is involved both in the formation of a 5′ cap structure and in termination of early transcription^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Vaccinia virus capping enzyme Related Antibodies
Appearance	Liquid
Color	Colorless to light yellow
SMILES	[Vaccinia virus capping enzyme]
Enzyme Activity	10 U/μL
Unit Definition	One unit is defined as the amount of enzyme that 10 pmol GTP to be fully incorporated into the 80 nt transcript product within 1 h at 37°C.
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Select Batch: Data Sheet (263 KB) SDS (251 KB) COA (241 KB) Handling Instructions (2659 KB)
References	[1]. Vos JC, et al. Vaccinia virus capping enzyme is a transcription initiation factor. EMBO J. 1991 Sep;10(9):2553-8. [Content Brief] [2]. Kyrieleis OJ, et al. Crystal structure of vaccinia virus mRNA capping enzyme provides insights into the mechanism and evolution of the capping apparatus. Structure. 2014 Mar 4;22(3):452-65. [Content Brief]