2. Cell Cycle/DNA Damage Cytoskeleton Apoptosis
  3. Microtubule/Tubulin Apoptosis
  4. Angustilongine M

Angustilongine M is a microtubule-targeting antitumor alkaloid (IC50=0.2 μM against HT-29 cells). Angustilongine M induces G0/G1 cell cycle arrest and mitochondrial apoptosis via tubulin polymerization promotion. Angustilongine M is promising for research of colorectal cancer and other solid tumors.

For research use only. We do not sell to patients.

Angustilongine M

Angustilongine M Chemical Structure

CAS No. : 2732914-43-9

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Angustilongine M Related Antibodies

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Description

Angustilongine M is a microtubule-targeting antitumor alkaloid (IC50=0.2 μM against HT-29 cells). Angustilongine M induces G0/G1 cell cycle arrest and mitochondrial apoptosis via tubulin polymerization promotion. Angustilongine M is promising for research of colorectal cancer and other solid tumors[1].

Molecular Weight

644.84

Formula

C41H48N4O3
CAS No.
SMILES

C[C@H]1C2=C(O[C@@]3([H])[C@]1([H])[C@@]4([H])[C@@]([C@]5([H])CC6=C(N(C7=CC=CC=C76)C)[C@](N5C)([H])C4)([H])CO3)C=CC8=C2C9=C([C@@]%10([H])[N@@]%11[C@@]([C@@H]([C@](/C(C%11)=C\C)([H])C%10)CO)([H])C9)N8C
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Angustilongine M Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Angustilongine M2732914-43-9Microtubule/TubulinApoptosisMicrotubuleHT-29 cellscolorectal cancerInhibitorinhibitorinhibit

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