2. GPCR/G Protein
  3. PTHR
  4. SW-106

SW-106 is a parathyroid hormone receptor 1 (PTHR1) antagonist. SW106 antagonizes PTHR1-mediated cAMP signaling induced by the peptide analog, M-PTH (1-11), as well as by the native PTH (1-9) sequence, as tethered to the extracellular end of transmembrane domain (TMD) helix-1 of the receptor. SW-106 can be used for the research of metabolic disease.

For research use only. We do not sell to patients.

SW-106

SW-106 Chemical Structure

CAS No. : 1027921-53-4

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SW-106 Related Antibodies

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Description

SW-106 is a parathyroid hormone receptor 1 (PTHR1) antagonist. SW106 antagonizes PTHR1-mediated cAMP signaling induced by the peptide analog, M-PTH (1-11), as well as by the native PTH (1-9) sequence, as tethered to the extracellular end of transmembrane domain (TMD) helix-1 of the receptor. SW-106 can be used for the research of metabolic disease[1].

IC50 & Target[1]

PTH1R

 

Molecular Weight

361.31

Formula

C17H16F5NO2
CAS No.
SMILES

O=C1NC2=CC=C(F)C(F)=C2[C@](C(F)(F)F)(/C=C/C3CC3)O[C@H]1CC
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SW-106 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SW-1061027921-53-4SW106SW 106PTHRParathyroid hormone receptorparathyroid hormone receptorPTHR1cAMPM-PTH (1-11)PTH (1-9)transmembrane domainmetabolic diseaseInhibitorinhibitorinhibit

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