2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. G7-18NATE TFA

G7-18NATE TFA is a peptide inhibitor of Grb7. G7-18NATE TFA binds to the Grb7-SH2 domain with micromolar affinity (Kd = 18.1 μM). G7-18NATE TFA inhibits cell proliferation, motility, cell invasion and 3D culture formation in several cancer cell lines.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

G7-18NATE TFA

G7-18NATE TFA Chemical Structure

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Based on 1 publication(s) in Google Scholar

Other Forms of G7-18NATE TFA:

G7-18NATE TFA Related Antibodies

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Description

G7-18NATE TFA is a peptide inhibitor of Grb7. G7-18NATE TFA binds to the Grb7-SH2 domain with micromolar affinity (Kd = 18.1 μM). G7-18NATE TFA inhibits cell proliferation, motility, cell invasion and 3D culture formation in several cancer cell lines[1][2].

In Vitro

G7-18NATE (10 μM, 24 h) inhibits cell migration in MDA-MB-468 cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

G7-18NATE TFA Related Antibodies
Molecular Weight

1417.50 (free base)

Formula

C67H80N14O19S.xC2HF3O2
Appearance

Solid

Color

White to off-white

Sequence

cyclo(CH2CO-Trp-Phe-Glu-Gly-Tyr-Asp-Asn-Thr-Phe-Pro-Cys(NH2)-S-)
Sequence Shortening

cyclo(CH2CO-WFEGYDNTFP-Cys(NH2)-S-)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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Purity & Documentation
References
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G7-18NATE TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

G7-18NATEEGFREpidermal growth factor receptorErbB-1HER1anticancerpeptideInhibitorinhibitorinhibit

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