Rab2 Antibody (YA5218)

Rab2 Antibody (YA5218) is a mouse-derived and non-conjugated monoclonal antibody, targeting to Rab2. It can be applicated for WB, ICC assays, in the background of human.

Rab2A belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis and are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rab2A is a membrane-bound protein and a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Rabs cycle between active GTP-bound and inactive GDP-bound states. In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology. Rab2A also regulates the compacted morphology of the Golgi.

P61019

Observed band size: 24 kDa

affinity chromatography.

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human

WB: 1:1000; ICC: 1:200

WB, ICC

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

Purified recombinant human Rab2 protein fragments expressed in E.coli.