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  3. Malvidin chloride

Malvidin chloride  (Synonyms: Syringidin)

Cat. No.: HY-122496 Purity: 97.05%
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Malvidin (chloride) is a bioactive compound isolated from grape. Malvidin shows cytotoxicity through the arrest of the G2/M phase of cell cycle and induction of apoptosis. Malvidin can be used for the research of cancer.

For research use only. We do not sell to patients.

Malvidin chloride

Malvidin chloride Chemical Structure

CAS No. : 643-84-5

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Based on 1 publication(s) in Google Scholar

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Description

Malvidin (chloride) is a bioactive compound isolated from grape. Malvidin shows cytotoxicity through the arrest of the G2/M phase of cell cycle and induction of apoptosis. Malvidin can be used for the research of cancer[1].

Cellular Effect
Cell Line Type Value Description References
RAW264.7 IC50
9 μM
Compound: Malvidin
Inhibition of ROS production in LPS-induced mouse RAW264.7 cells incubated for 22 hrs by H2DCF-DA staining based analysis
Inhibition of ROS production in LPS-induced mouse RAW264.7 cells incubated for 22 hrs by H2DCF-DA staining based analysis
[PMID: 35932905]
RAW264.7 IC50
9 μM
Compound: Malvidin
Inhibition of LPS-stimulated ROS production in mouse RAW264.7 cells after 22 hrs by C-400 fluorescent dye-based assay
Inhibition of LPS-stimulated ROS production in mouse RAW264.7 cells after 22 hrs by C-400 fluorescent dye-based assay
[PMID: 28159411]
RAW264.7 IC50
9 μM
Compound: Malvidin
Inhibition of LPS-stimulated ROS production in mouse RAW264.7 cells preincubated for 1 hr followed by LPS stimulation after 24 hrs by CMH2DCFDA probe-based fluorescence assay
Inhibition of LPS-stimulated ROS production in mouse RAW264.7 cells preincubated for 1 hr followed by LPS stimulation after 24 hrs by CMH2DCFDA probe-based fluorescence assay
[PMID: 28384544]
In Vitro

Malvidin (0~80 μg/mL; 96 hours; U937 cells) shows cytotoxic activity in a dose-dependent pattern[1].
The IC50 value of Malvidin for U937 cells is 40 μg/mL. Malvidin (U937 cells) shows arrest at the G2/M phase of the cell cycle and increases sub G1 hypo-diploid population[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: U937 cells
Concentration: 0~80 μg/mL
Incubation Time: 96 hours
Result: Showed cytotoxic activity in a dose-dependent pattern.
Molecular Weight

366.75

Formula

C17H15ClO7

CAS No.
Appearance

Solid

Color

Brown to dark brown

SMILES

OC1=CC(O)=C2C=C(C(C3=CC(OC)=C(C(OC)=C3)O)=[O+]C2=C1)O.[Cl-]

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Malvidin chloride
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HY-122496
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