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Results for "

Duchenne's muscular dystrophy

" in MedChemExpress (MCE) Product Catalog:

9197

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34

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75

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231

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559

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6

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109

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1032

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589

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701

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175

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119

Click Chemistry

165

Oligonucleotides

Cat. No. Product Name Classification
  • HY-108753A
    Eteplirsen sodium

    AVI 4658 sodium

    		 Antisense Oligonucleotides
    Eteplirsen (AVI 4658) sodium is a synthetic antisense oligonucleotide that induces dystrophin production. Eteplirsen (AVI 4658) sodium promotes exon 51 skipping in Duchenne muscular dystrophy patients and can be used in Duchenne muscular dystrophy research .
  • HY-108753
    Eteplirsen

    AVI 4658

    		 Antisense Oligonucleotides
    Eteplirsen (AVI 4658) is a synthetic antisense oligonucleotide. Eteplirsen can be used for Duchenne muscular dystrophy research .
  • HY-132611A
    Golodirsen sodium

    SRP-4053 sodium

    		 Antisense Oligonucleotides
    Golodirsen sodium is a phosphorodiamidate morpholino oligomer (PMO) that specifically targets exon 53 of dystrophin pre-mRNA. Golodirsen sodium can be used for the research of Duchenne muscular dystrophy (DMD) .
  • HY-132611
    Golodirsen

    SRP-4053

    		 Antisense Oligonucleotides
    Golodirsen (SRP-4053) is a phosphorodiamidate morpholino oligomer (PMO) that specifically targets exon 53 of dystrophin pre-mRNA. Golodirsen can be used for the research of Duchenne muscular dystrophy (DMD) .
  • HY-127137A
    Adenylosuccinic acid tetraammonium

    Adenylosuccinate tetraammonium; Aspartyl adenylate tetraammonium

    		 Nucleotides and their Analogs
    Adenylosuccinic acid tetraammonium (Adenylosuccinate; Aspartyl adenylate) is an orally active purine ribonucleoside monophosphate and plays a role in nucleotide cycle metabolite. Adenylosuccinic acid tetraammonium can be converted into fumaric acid through adenylosuccinate lyase. Adenylosuccinic acid tetraammonium has the potential for the study of duchenne muscular dystrophy(DMD) .
  • HY-132586A
    Viltolarsen sodium

    NS-065/NCNP-01 sodium

    		 Antisense Oligonucleotides
    Viltolarsen (NS-065/NCNP-01) sodium is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen sodium binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen sodium has the potential for Duchenne muscular dystrophy (DMD) research .
  • HY-132592
    Suvodirsen

    WVE-210201

    		 Antisense Oligonucleotides
    Suvodirsen (WVE-210201) is a oligonucleotide. Suvodirsen has the potential for study Duchenne muscular dystrophy (DMD) .
  • HY-132592A
    Suvodirsen sodium

    WVE-210201 sodium

    		 Antisense Oligonucleotides
    Suvodirsen sodium induces exon 51 skipping and has the potential for study Duchenne muscular dystrophy (DMD) .
  • HY-132585A
    SRP-5051 sodium

    Vesleteplirsen sodium

    		 Antisense Oligonucleotides
    SRP-5051 sodium is a next-generation antisense oligonucleotide of peptide phosphorodiamidate morpholino oligomer (PPMO). SRP-5051 targeting exon 51 skipping in Duchenne muscular dystrophy (DMD) .
  • HY-132586
    Viltolarsen

    NS-065/NCNP-01

    		 Antisense Oligonucleotides
    Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen has the potential for Duchenne muscular dystrophy (DMD) research .
  • HY-132584A
    Casimersen sodium

    SRP-4045 sodium

    		 Antisense Oligonucleotides
    Casimersen sodium is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen sodium binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen sodium can be used for the research of Duchenne muscular dystrophy (DMD) .
  • HY-132584
    Casimersen

    SRP-4045

    		 Antisense Oligonucleotides
    Casimersen (SRP-4045) is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen can be used for the research of Duchenne muscular dystrophy (DMD) .
  • HY-145724A
    Drisapersen sodium

    Kyndrisa sodium; GSK2402968A sodium; PRO051 sodium

    		 Antisense Oligonucleotides
    Drisapersen sodium, a antisense oligonucleotide, induces exon 51 skipping during dystrophin pre-mRNA splicing and allows synthesis of partially functional dystrophin in Duchenne muscular dystrophy (DMD) patients with amenable mutations.
  • HY-145724
    Drisapersen

    Kyndrisa; GSK2402968A; PRO051

    		 Antisense Oligonucleotides
    Drisapersen, a antisense oligonucleotide, induces exon 51 skipping during dystrophin pre-mRNA splicing and allows synthesis of partially functional dystrophin in Duchenne muscular dystrophy (DMD) patients with amenable mutations.
  • HY-150237
    FITC-labeled Drisapersen sodium

    		Antisense Oligonucleotides
    FITC-labeled Drisapersen (sodium) is Drisapersen labeled with FITC. Drisapersen, a antisense oligonucleotide, induces exon 51 skipping during dystrophin pre-mRNA splicing and allows synthesis of partially functional dystrophin in Duchenne muscular dystrophy (DMD) patients with amenable mutations.
  • HY-153324
    PS220 sodium

    		Antisense Oligonucleotides
    PS220 (sodium) is an antisense RNA oligonucleotides. PS220 (sodium) can be used for research of treating muscular dystrophy .
  • HY-132593
    Rovanersen

    WVE-120101

    		 Antisense Oligonucleotides
    Rovanersen (WVE-120101) is an antisense oligonucleotide that specifically targets mutated mRNA copies of the huntington (HTT) gene without affecting healthy mRNA of HTT gene, thereby preventing the production of faulty Huntingtin protein. Rovanersen can be used for huntington’s disease research .
  • HY-148457
    Avacincaptad pegol

    		Aptamers
    Avacincaptad pegol, which is a pegylated aptamer, has garnered significant attention as a C5 complement inhibitor that may reduce inflammation-related retinal pigment epithelium (RPE) damage. Avacincaptad pegol caqn be used for the research of stargardt macular dystrophy (STGD1) and geographic atrophy (GA) .
  • HY-145725A
    Baliforsen

    ISIS 598769; IONIS 598769; BIIB 065; ISIS-DMPK-2.5Rx

    		 Antisense Oligonucleotides
    Baliforsen is an antisense oligonucleotide (16 nucleotides) designed to target myotonic dystrophy protein kinase (DMPK) mRNA and research myotonic dystrophy.
  • HY-145725
    Baliforsen sodium

    IONIS 598769 sodium; ISIS 598769 sodium

    		 Antisense Oligonucleotides
    Baliforsen (sodium) is an antisense oligonucleotide (16 nucleotides) designed to target myotonic dystrophy protein kinase (DMPK) mRNA and research myotonic dystrophy.
  • HY-Y1069
    (S)-Malic acid
    1 Publications Verification

    (S)-Hydroxybutanedioic acid; (S)-E 296; L-Malic acid

    		 Flavoring Agents
    (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive.
  • HY-160062
    S2.2 aptamer sodium

    		Aptamers
    S2.2 aptamer sodium is a nucleic acid aptamer targeting the mucin MUC1 and can be used for targeted imaging of MCF-7 cancer cells. S2.2 aptamer sodium was labeled with Cy5, and when fluorescent silicon nanodots (SiND) were present, the fluorescence was quenched; when MUC1 was also present, the fluorescence was restored. S2.2 aptamer sodium detects MUC1 with a linear range of 3.33-250 nM .
  • HY-145728B
    (R/S)-Alicaforsen

    (R/S)-ISIS-2302

    		 Antisense Oligonucleotides
    (R/S)-Alicaforsen is the racemate of Alicaforsen composed of R and S configurations. Alicaforsen is a 20-base antisense oligonucleotide inhibiting ICAM-1 production, which is an important adhesion molecule involved in leukocyte migration and trafficking to the site of inflammation.
  • HY-153372
    93-O17S

    		Cationic Lipids
    93-O17S is a chalcogen-containing ionizable cationic lipid used for making lipid nanoparticles (LNPs).
  • HY-147332
    TCL053

    		Cationic Lipids
    TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle .
  • HY-145969
    β-S-ARCA

    		Cap Analogs
    β-S-ARCA is a mRNA 7-methylguanosine (m 7G) cap analog carrying a phosphorothioate (PS) moiety. mRNAs incorporating β-S-ARCA have elongated cellular half-lives and showed augmented protein expression. β-S-ARCA D1 has been applied in researching experimental mRNA-based anticancer vaccines .
  • HY-R01697
    hsa-miR-548s mimic

    		MicroRNAs miRNA mimics
    hsa-miR-548s mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
  • HY-120967A
    (2S)-OMPT

    		Phospholipids
    (2S)-OMPT triethylamine, a chiral oxirane derivative, is commonly used as a ligand in asymmetric catalysis, especially in the enantioselective synthesis of bioactive molecules such as amino acids and drugs. (2S)-OMPT triethylamine has unique chemical properties that allow it to selectively bind certain metal complexes and activate them in a way that favors the formation of specific enantiomers.
  • HY-RI01697
    hsa-miR-548s inhibitor

    		MicroRNAs miRNA inhibitors
    hsa-miR-548s inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
  • HY-A0104
    HPMC (Viscosity:11250-21000mPa.s)
    3 Publications Verification

    Hypromellose (Viscosity:11250-21000mPa.s); (Hydroxypropyl)methyl cellulose (Viscosity:11250-21000mPa.s); Celacol HPM 5000 (Viscosity:11250-21000mPa.s)

    		 Thickeners Suspending Agents
    HPMC (Viscosity:11250-21000mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices.
  • HY-Y0703
    Sodium carboxymethyl cellulose (Viscosity:800-1200 mPa.s)
    Maximum Cited Publications
    23 Publications Verification

    CMC-Na (Viscosity:800-1200 mPa.s)

    		 Binders Disintegrants Suspending Agents
    Sodium carboxymethyl cellulose (Viscosity:800-1200 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.
  • HY-R01697A
    hsa-miR-548s agomir

    		MicroRNAs miRNA agomirs
    hsa-miR-548s agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
  • HY-RS24256
    C1s Rat Pre-designed siRNA Set A

    		siRNAs Rat Pre-designed siRNA Sets
    C1s Rat Pre-designed siRNA Set A contains three designed siRNAs for C1s gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS23418
    S100b Rat Pre-designed siRNA Set A

    		siRNAs Rat Pre-designed siRNA Sets
    S100b Rat Pre-designed siRNA Set A contains three designed siRNAs for S100b gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS07882
    LTC4S Human Pre-designed siRNA Set A

    		siRNAs Human Pre-designed siRNA Sets

    LTC4S Human Pre-designed siRNA Set A contains three designed siRNAs for LTC4S gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

  • HY-RS24472
    Ube2s Rat Pre-designed siRNA Set A

    		siRNAs Rat Pre-designed siRNA Sets
    Ube2s Rat Pre-designed siRNA Set A contains three designed siRNAs for Ube2s gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS08031
    MAP1S Human Pre-designed siRNA Set A

    		siRNAs Human Pre-designed siRNA Sets

    MAP1S Human Pre-designed siRNA Set A contains three designed siRNAs for MAP1S gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

  • HY-RS12389
    S100P Human Pre-designed siRNA Set A

    		siRNAs Human Pre-designed siRNA Sets

    S100P Human Pre-designed siRNA Set A contains three designed siRNAs for S100P gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

  • HY-RS07904
    LY6S Human Pre-designed siRNA Set A

    		siRNAs Human Pre-designed siRNA Sets

    LY6S Human Pre-designed siRNA Set A contains three designed siRNAs for LY6S gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

  • HY-RS18000
    Ube2s Mouse Pre-designed siRNA Set A

    		siRNAs Mouse Pre-designed siRNA Sets
    Ube2s Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ube2s gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS01737
    C1S Human Pre-designed siRNA Set A

    		siRNAs Human Pre-designed siRNA Sets

    C1S Human Pre-designed siRNA Set A contains three designed siRNAs for C1S gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

  • HY-RS12390
    S100Z Human Pre-designed siRNA Set A

    		siRNAs Human Pre-designed siRNA Sets

    S100Z Human Pre-designed siRNA Set A contains three designed siRNAs for S100Z gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

  • HY-RS12387
    S100B Human Pre-designed siRNA Set A

    		siRNAs Human Pre-designed siRNA Sets

    S100B Human Pre-designed siRNA Set A contains three designed siRNAs for S100B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

  • HY-RS15361
    UBE2S Human Pre-designed siRNA Set A

    		siRNAs Human Pre-designed siRNA Sets

    UBE2S Human Pre-designed siRNA Set A contains three designed siRNAs for UBE2S gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

  • HY-RS12388
    S100G Human Pre-designed siRNA Set A

    		siRNAs Human Pre-designed siRNA Sets

    S100G Human Pre-designed siRNA Set A contains three designed siRNAs for S100G gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

  • HY-RS21637
    Ltc4s Mouse Pre-designed siRNA Set A

    		siRNAs Mouse Pre-designed siRNA Sets
    Ltc4s Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ltc4s gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS01800
    CACNA1S Human Pre-designed siRNA Set A

    		siRNAs Human Pre-designed siRNA Sets

    CACNA1S Human Pre-designed siRNA Set A contains three designed siRNAs for CACNA1S gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

  • HY-RS16975
    S100b Mouse Pre-designed siRNA Set A

    		siRNAs Mouse Pre-designed siRNA Sets
    S100b Mouse Pre-designed siRNA Set A contains three designed siRNAs for S100b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS21234
    Cacna1s Mouse Pre-designed siRNA Set A

    		siRNAs Mouse Pre-designed siRNA Sets
    Cacna1s Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cacna1s gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS16593
    S100a8 Mouse Pre-designed siRNA Set A

    		siRNAs Mouse Pre-designed siRNA Sets
    S100a8 Mouse Pre-designed siRNA Set A contains three designed siRNAs for S100a8 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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