S-(p-Nitrobenzyl)glutathione

Cat. No.: HY-148208 Purity: 98.99%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

S-(p-Nitrobenzyl)glutathione is a competitive glutathionase inhibitor. S-(p-Nitrobenzyl)glutathione is converted to the corresponding cysteine derivatives by rat kidney microsomes. S-(p-Nitrobenzyl)glutathione can be used for the research of metabolic breakdown of glutathione by the glutathionase system.

For research use only. We do not sell to patients.

S-(p-Nitrobenzyl)glutathione Chemical Structure

CAS No. : 6803-19-6

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

442.44

Formula

C₁₇H₂₂N₄O₈S

CAS No.

6803-19-6

Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)CCC(N[C@H](C(NCC(O)=O)=O)CSCC1=CC=C(C=C1)[N+]([O-])=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (113.01 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2602 mL	11.3010 mL	22.6019 mL
5 mM	0.4520 mL	2.2602 mL	4.5204 mL
10 mM	0.2260 mL	1.1301 mL	2.2602 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.99%

Select Batch:

Data Sheet (272 KB) SDS (251 KB)

COA (249 KB) HNMR (298 KB) LCMS (102 KB)

Handling Instructions (2659 KB)

References

[1]. I García-Sáez, et al. Molecular structure at 1.8 A of mouse liver class pi glutathione S-transferase complexed with S-(p-nitrobenzyl)glutathione and other inhibitors. J Mol Biol. 1994 Apr 1;237(3):298-314. [Content Brief]

[2]. T Suga, et al. Studies on mercapturic acids. Participation of glutathionase in the conversion of glutathione derivatives to cysteine derivatives. J Biochem. 1966 Aug;60(2):133-9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.2602 mL	11.3010 mL	22.6019 mL	56.5048 mL
	5 mM	0.4520 mL	2.2602 mL	4.5204 mL	11.3010 mL
	10 mM	0.2260 mL	1.1301 mL	2.2602 mL	5.6505 mL
	15 mM	0.1507 mL	0.7534 mL	1.5068 mL	3.7670 mL
	20 mM	0.1130 mL	0.5650 mL	1.1301 mL	2.8252 mL
	25 mM	0.0904 mL	0.4520 mL	0.9041 mL	2.2602 mL
	30 mM	0.0753 mL	0.3767 mL	0.7534 mL	1.8835 mL
	40 mM	0.0565 mL	0.2825 mL	0.5650 mL	1.4126 mL
	50 mM	0.0452 mL	0.2260 mL	0.4520 mL	1.1301 mL
	60 mM	0.0377 mL	0.1883 mL	0.3767 mL	0.9417 mL
	80 mM	0.0283 mL	0.1413 mL	0.2825 mL	0.7063 mL
	100 mM	0.0226 mL	0.1130 mL	0.2260 mL	0.5650 mL